Gel Permeation Chromatography (GPC) Analysis Pricing Guide: What Affects the Cost?

GPC Analysis Cost

Introduction: Understanding GPC Analysis Cost from the Start

If you’re working in polymer research or quality control, knowing the GPC analysis cost is essential. Whether you’re in a university lab, a manufacturing company, or part of a regulatory body, it helps to understand what affects pricing. At ResolveMass Laboratories Inc., we believe in clear and honest pricing to help you make informed decisions.

Running a GPC test involves high-end instruments and trained experts, which adds to the cost. But choosing quality analysis can save you both time and resources later. Our goal is not just to give results—but to provide data you can trust.

To learn more about the basics, explore our in-depth guide on What is Gel Permeation Chromatography.


What Is Gel Permeation Chromatography (GPC)?

Gel Permeation Chromatography (GPC), also called Size Exclusion Chromatography (SEC), is a testing method used to measure the molecular weight and size distribution of polymers. It separates polymer molecules based on their size using special columns filled with porous material.

GPC is commonly used in research and production of plastics, biodegradable materials, and specialty polymers. It helps ensure product stability and supports development of new polymer formulations. For regulated industries, GPC is often required to validate materials for compliance.


Key Factors That Influence GPC Analysis Cost

1. Sample Type and Preparation Effort

The type of polymer you’re testing can affect how much work is needed before running the analysis. For example, biodegradable polymers like PLGA or PCL may need special solvents or longer prep times. These steps increase labor and material costs.

At ResolveMass, we’re skilled at handling tricky samples and use tried-and-tested procedures to make sure your data is accurate.


2. Number of Samples Submitted

The GPC analysis cost per sample can drop when you send multiple samples together. One sample might cost around USD $300 to $800, but submitting 10 or more can bring the price down by up to 30%.

Bulk testing helps us save time and resources, and we pass those savings on to you. Planning your batch submissions ahead of time is a great way to stay on budget.


3. Type of Calibration Standards

High-quality results depend on using the right calibration standards. Common ones include polystyrene or PMMA. For new or unusual polymers, custom calibration curves may be needed—and those cost a bit more.

We offer both standard and custom calibration options based on your polymer type. Custom curves give better accuracy for materials that don’t match traditional standards. Our facility offers custom GPC calibration standards for unique polymer systems.


4. Detector Type Used in Testing

Basic GPC tests use Refractive Index (RI) detectors, which are more affordable. But for deeper insights, we may use advanced tools like Multi-Angle Light Scattering (MALS) or viscometers. These offer better data but require more setup and cost more.

These tools are ideal for detecting structural details and absolute molecular weights, especially in complex polymer blends. Check out our services in GPC for polymer characterization for advanced configurations.


5. Turnaround Time Requested

If you need results urgently (within 1–2 days), the GPC analysis cost will increase. Faster service means rescheduling lab work, longer hours, and prioritizing your sample, which comes at a premium.

Choosing our regular service (typically 5–7 business days) is more budget-friendly. We recommend early planning to avoid paying extra for express results.


6. Solubility Challenges and Custom Method Development

Some polymers don’t dissolve easily and may require special solvents or methods. Developing a new testing method takes time and resources, which adds to the cost.

Our experts can create custom testing plans for difficult samples to ensure the most accurate and repeatable results. We specialize in such cases—see GPC analysis of polymers for how we approach such challenges.


7. Regulatory Requirements (GMP/GLP)

If your testing must follow Good Manufacturing Practices (GMP) or Good Laboratory Practices (GLP), this increases the complexity of the work. Strict documentation, added checks, and official protocols all raise the GPC analysis cost.

ResolveMass supports regulated industries like pharma and medical devices by offering fully compliant services.


Why Choose ResolveMass? More Than Just a Test Lab

At ResolveMass Laboratories Inc., we’ve been specializing in polymer testing for over 15 years. We don’t just give numbers—we help interpret the results, design testing methods, and provide guidance at every step.

Our team includes PhD chemists, and we use cutting-edge equipment. Whether you’re analyzing basic plastics or advanced biodegradable materials, we’re here to support your project fully.

Explore our comparison of GPC vs SEC to better understand our analytical approach.


Clear and Transparent Quotes

When you request a quote from us, we break down every cost. No hidden fees—just honest pricing. Here’s what we include:

  • Sample preparation (if needed)
  • Calibration (standard or custom)
  • Detector use (RI, MALS, etc.)
  • Method development (for novel polymers)
  • Rush service charges (if applicable)

This clarity makes it easier for you to plan your project budget. See our complete GPC analysis service page for more.


How to Keep GPC Costs Lower Without Losing Quality

  • Submit in bulk: Sending more samples lowers your cost per test.
  • Use common polymers: Standard materials need less customization.
  • Avoid urgent requests: Give yourself enough time to use standard turnaround.
  • Talk to us early: We’ll suggest the most cost-effective options.

By using these tips, you can keep your GPC analysis cost manageable while still getting high-quality data.

To get a tailored quote, visit our Contact Us page today.



Conclusion: GPC Cost Reflects Quality and Expertise

The price of GPC testing depends on many factors, including sample type, complexity, and how fast you need the results. But more than just cost, it represents the value of expert guidance, precise tools, and trustworthy data.

At ResolveMass Laboratories Inc., we focus on delivering high-quality analysis with honest pricing. When accurate polymer data matters, choosing the right lab can make all the difference.

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Top Frequently Asked Questions (FAQs) on GPC Analysis Cost

How much does a GPC cost?

The cost of a single GPC (Gel Permeation Chromatography) analysis usually ranges from USD $300 to $800 per sample. The final price depends on factors like the type of polymer, number of samples, calibration needs, and turnaround time. Bulk testing can reduce the cost per sample.

What is the cost of a GPC column?

A GPC column can cost anywhere from CAD $1,000 to $8,000, depending on its material, size, and quality. Columns designed for high precision or specific polymer types are usually more expensive. They also need proper care to last longer and maintain accuracy.

What sector is GPC?

GPC is mainly used in the polymer science sector, which includes industries like plastics, chemicals, pharmaceuticals, and materials research. It also plays a role in biomedical and regulatory fields where accurate polymer testing is required for product approval and safety.

Is GPC HPLC?

GPC is a type of HPLC (High-Performance Liquid Chromatography), but it has a different purpose. While regular HPLC separates substances by their chemical interactions, GPC separates molecules by size. So, GPC is a special form of HPLC made for polymer analysis.

How to analyse GPC data?

To analyze GPC data, you look at the molecular weight distribution of the polymer. The output graph shows how many molecules are present at each size. Key values like Mn, Mw, and polydispersity index are calculated to understand the polymer’s structure and quality.

What is data analysis of gel permeation chromatography?

GPC data analysis involves studying the curve that shows how polymer chains are distributed by size. From this curve, scientists calculate important values that describe the average molecular weight and consistency of the sample. This helps in judging the material’s strength and performance.

Is GPC analysis cost higher for biodegradable polymers?

Yes, the GPC analysis cost is usually higher for biodegradable polymers. These materials often need special solvents, longer preparation time, and sometimes custom calibration, which increases both effort and cost. Extra steps are taken to ensure accurate and reliable results.

References

  1. GPC/SEC as a Key Tool for Assessment of Polymer Quality and Determination of Macromolecular Properties
  2. Cross-Industry Issues in Nanomanufacturing

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