OVERVIEW of Pyrrole-d5 | CAS 18430-85-8
Pyrrole-d5 (CAS 18430-85-8) is a fully deuterated analogue of pyrrole, containing five deuterium atoms uniformly incorporated into the heterocyclic ring. This isotopic substitution provides enhanced mass resolution and clear spectral separation, making it a highly reliable internal standard for GC-MS, LC-MS, NMR spectroscopy, and kinetic isotope studies.
With exceptional stability and chemical equivalence to native pyrrole, Pyrrole-d5 is widely used in pharmaceutical development, environmental testing, forensic toxicology, and mechanistic organic chemistry. ResolveMass Laboratories Inc. supplies this compound with high isotopic enrichment and purity, ensuring reproducible performance across analytical applications.
CHEMICAL INFORMATION
Chemical Name: Pyrrole-d5
Synonyms: Deuterated pyrrole, Pyrrolidine-d5 precursor
CAS Number: 18430-85-8
Molecular Formula: C₄D₅N
Molecular Weight: 72.12 g/mol
Isotopic Enrichment: ≥98 atom % D
Functional Groups: Aromatic heterocycle (pyrrole ring)
APPLICATIONS of Pyrrole-d5 | CAS 18430-85-8
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Internal Standard for LC-MS & GC-MS: Enables accurate quantitation of pyrrole-containing compounds and nitrogen heterocycles.
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NMR Spectroscopy: Used as a reference material and for structural studies of pyrrolic derivatives.
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Pharmaceutical R&D: Supports impurity profiling, metabolite identification, and synthesis validation.
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Environmental & Toxicology Analysis: Useful for monitoring pyrrolic contaminants and volatile nitrogen species.
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Isotope Effect & Mechanistic Studies: Deuterium incorporation allows investigation of reaction pathways and kinetic isotope effects.
FEATURES & BENEFITS
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High Isotopic Purity: Ensures strong mass spectral separation and accurate quantitation.
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Excellent Chemical Stability: Suitable for long-term storage and robust analytical workflows.
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Structural Equivalence to Native Pyrrole: Makes it ideal for isotope-dilution analysis.
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Low Background Interference: Provides clean spectra even in complex matrices.
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Versatile Analytical Use: Supports MS, NMR, organic synthesis, and mechanistic research.
SUMMARY
Pyrrole-d5 (CAS 18430-85-8) is a fully deuterated heterocycle widely used as an internal standard in mass spectrometry, NMR, and mechanistic studies. Its high isotopic enrichment and chemical purity make it invaluable for quantitative analysis, impurity detection, and kinetic investigations. ResolveMass Laboratories Inc. provides Pyrrole-d5 with consistent quality suitable for research, pharmaceutical, and environmental applications.
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