Deuterated Methyl methacrylate-d8 | CAS 35233-69-3

PRODUCT OVERVIEW

 

Deuterated Methyl methacrylate-d8 | CAS 35233-69-3 , is a fully deuterated isotopologue of methyl methacrylate in which all eight hydrogen atoms have been replaced with deuterium. This stable, non‑radioactive deuterated solvent and reagent is widely used in analytical chemistry, nuclear magnetic resonance (NMR) spectroscopy, mass spectrometry, and specialized polymer research. It is particularly valuable for studies requiring minimal proton background interference, precise molecular characterization, isotopic labeling, and dynamic analysis of polymers.

ResolveMass Laboratories Inc. offers high‑purity MMA‑d8 designed to meet demanding research and industrial applications where isotopic integrity and trace impurity control are paramount. Each batch is subject to rigorous quality control to ensure deuterium incorporation, purity, and consistency.

---

CHEMICAL IDENTITY

• Chemical Name: Deuterated Methyl Methacrylate‑d8

• CAS Number: 35233‑69‑3

• Molecular Formula: C5D8O2

• Molecular Weight: 108.7 g/mol (approx)

• Deuterium Content: ≥ 99% D incorporation

• Appearance: Clear, colorless liquid

• Synonyms:

  • MMA‑d8

  • Methacrylic acid, methyl ester‑d8

  • Deuterated MMA

---

KEY APPLICATIONS  of  Deuterated Methyl methacrylate-d8 | CAS 35233-69-3

 

NMR SPECTROSCOPY

Deuterated Methyl Methacrylate‑d8 is extensively used as a solvent and standard in ^1H and ^13C NMR experiments due to its deuterium content, which significantly reduces proton signals that can otherwise obscure sample spectra. Its replacement of hydrogen with deuterium makes it ideal for high‑resolution NMR solvent applications, particularly when studying proton‑rich samples where spectral clarity is essential.

ISOTOPE LABELING STUDIES

In advanced organic and polymer chemistry, MMA‑d8 serves as an isotopic label in mechanistic studies, enabling:

• Tracking of reaction pathways

• Determination of kinetic isotope effects

• Investigation of radical and anionic polymerization mechanisms

Deuterium incorporation allows researchers to distinguish between unlabeled and labeled molecules in complex mixtures.

MASS SPECTROMETRY RESEARCH

The unique mass shift of deuterated compounds makes MMA‑d8 a preferred internal standard in GC‑MS and LC‑MS methodologies. Its predictable mass differences enhance the accuracy of quantitative analyses and calibration curves, enabling improved detection limits and performance in complex matrices.

POLYMER SCIENCE

MMA‑d8 is used in the synthesis of deuterated polymethyl methacrylate (PMMA‑d8) and copolymers for:

• Structural studies via neutron scattering

• Material characterization

• Polymer aging and degradation research

• Molecular dynamics simulations

Isotopically labeled polymers are essential tools in research on morphology, chain dynamics, and mechanical properties without altering fundamental chemistry.

CHEMICAL KINETICS & MECHANISTIC INVESTIGATION

Researchers use MMA‑d8 in chemical kinetic studies to probe reaction rates and mechanisms influenced by isotopic substitution. The kinetic isotope effect (KIE) arising from deuterium substitution can offer insight into bond breakage and formation steps, transition states, and reaction intermediates.

---

QUALITY ASSURANCE

At ResolveMass Laboratories Inc., every lot of MMA‑d8 is analyzed using state‑of‑the‑art techniques to verify:

• Deuterium incorporation level

• Organic impurity profile

• Water content

• Volatile and non‑volatile contaminants

Quality testing includes NMR spectroscopy, GC/MS, and high‑performance liquid chromatography (HPLC) to ensure material meets stringent research and application demands.

---

PACKAGING OPTIONS

Deuterated Methyl Methacrylate‑d8 is available in a range of laboratory‑friendly packaging sizes to suit research, scale‑up, and production needs:

• 10 mL amber glass vials

• 50 mL reagent bottles

• 100 mL sealed ampoules

• Custom packaging available upon request

All containers are sealed under inert conditions where required to preserve isotopic and chemical integrity.

---

CUSTOM SERVICES & SUPPORT

ResolveMass Laboratories Inc. offers tailored services including:

• Custom isotopic labeling (partial deuteration patterns)

• Bulk scaling

• Technical support for analytical method integration

• Certificates of Analysis (CoA) and traceability documentation

Contact our technical team for project consultation and ordering guidance.