Resolving Complex Drug Development Challenges through Specialized CRO and CDMO support
What We do?
Generic and Novel Drug Development Services
We support pharmaceutical R&D with high-complexity IND and ANDA projects, including:
Custom Synthesis
We support pharmaceutical R&D with high-complexity synthesis projects, including:
- Custom API / intermediate synthesis
- Custom Polymer Synthesis
- Forced-degradation impurity synthesis
- Peptide-oligonucleotide conjugation (POCs)
- Custom polymer building blocks for drug-delivery research
Polymer synthesis and Characterization for Pharma Projects
PLGA, PLA, PCL, PEG-copolymers, and novel polymer architectures used in drug delivery
- GPC/SEC molecular weight & polydispersity analysis
- NMR block-length determination
- FTIR structural verification
- DSC/TGA thermal analysis
Mass Spectrometry Based Analytical Services
- Nitrosamine Testing & Regulatory Compliance
- Extractables & Leachables (E&L) Testing
- High-Resolution Mass Spectrometry & Structural Elucidation
- Gas Chromatography Mass Spectrometry (GCMS) Analysis
- Impurity Identification and Characterization
We take on the molecules other labs hand back.
ResolveMass is a Canadian CRO and CDMO built around one idea: complex pharmaceutical projects — peptides, engineered polymers, controlled-release systems — need one team that can carry them from synthesis to submission, not four vendors that each own a piece of the problem.
GMP-compliant under Health Canada. FDA-registered. ISO 9001:2015 certified.
“We built the lab we wished we’d had — one place where a difficult molecule doesn’t have to change hands four times to get an answer.”
ResolveMass Laboratories was founded in Laval, Québec, by chemists and analytical scientists who spent their careers on the harder end of drug development — peptide-oligonucleotide conjugates, novel polymer architectures, controlled-release formulations. That kind of work tends to stall inside labs built for routine small-molecule projects, passed between separate synthesis, analytical, and formulation vendors that don’t share context.
So we set up ResolveMass differently: custom synthesis, formulation development, polymer science, and mass spectrometry sit inside one team, working from the same data. It’s a structure built for the questions our clients actually bring us, not for a standard workflow they have to fit into.
Deliver top-tier contract research and development across complex drug development, polymer synthesis, and analytical chemistry — so our partners can move a breakthrough from bench to patient.
Set the standard for how complex, novel drug-delivery projects get developed: precise, transparent, and built around the molecule — not around a standard workflow.
One team, four disciplines
Most projects touch more than one of these — that’s the point. Nothing here is handed off to a separate vendor.
Drug Discovery & Generic Development
- Formulation & analytical development, novel and generic
- Regulatory support for IND and ANDA projects
- Peptide programs — semaglutide, liraglutide, tirzepatide, lanreotide, nusinersen
Custom Synthesis
- Custom API and intermediate synthesis
- Forced-degradation impurity synthesis
- Peptide-oligonucleotide conjugation (POCs)
Polymer Science
- PLGA, PLA, PCL, PEG-copolymers & novel architectures
- Molecular weight & polydispersity analysis
- NMR, FTIR, DSC/TGA characterization
Mass Spectrometry & Analytics
- HRMS exact-mass & structural elucidation
- Bioanalytical, biomarker, proteomic, lipidomic & metabolomic services
- Signature testing lines below — peptide, nitrosamine & E&L
Where clients bring us the hardest questions
These three lines account for most of what lands on our bench first — the testing that’s hardest to source elsewhere.
Peptide Characterization
Sequence verification, modification detection, and stability-indicating methods for GLP-1s and other complex peptide APIs.
- Structural confirmation & sequence mapping
- Oxidation, deamidation, truncation & aggregate ID
- Forced degradation & batch-to-batch consistency
Nitrosamine Testing
Trace-level detection of nitrosamine drug substance-related impurities (NDSRIs), with risk assessment built into the same engagement.
- Chemical & structural risk assessment
- Screening & control method development
- Batch-to-batch monitoring & filing support
Extractables & Leachables
Full E&L programs across packaging, delivery systems, and manufacturing contact materials — from risk assessment to safety qualification.
- Systematic extractables studies, multi-solvent & thermal
- Leachables monitoring, accelerated & real-time
- Toxicological risk assessment & reporting
What that structure gets you
No context lost between vendors
Synthesis, formulation, polymer science, and mass spec run from the same lab and the same dataset — nothing gets re-explained to a new contractor mid-project.
Built for the difficult cases
Peptide conjugates, engineered polymers, and controlled-release systems are the daily work here, not an exception request.
PhD scientists on the bench
Projects are run by the chemists and analytical scientists doing the work, not relayed through account managers.
Canadian-based, globally qualified
GMP-compliant under Health Canada, FDA-registered, and ISO 9001:2015 certified — the regulatory bar our clients need wherever they file.
One lab. Global reach. Every project under NDA.
Every engagement is confidential by default — that’s also why you won’t find client logos on this page. What we can show you is where the work goes:
Have a molecule that needs more than a standard workflow?
Book a call with our scientific team and walk through the project directly with the chemists who’d run it.
Book a Meeting