Resolving Complex Drug Development Challenges through Specialized CRO and CDMO support

What We do?

01

Generic and Novel Drug Development Services

We support pharmaceutical R&D with high-complexity IND and ANDA projects, including:

02

Custom Synthesis

We support pharmaceutical R&D with high-complexity synthesis projects, including:

03

Polymer synthesis and Characterization for Pharma Projects

PLGA, PLA, PCL, PEG-copolymers, and novel polymer architectures used in drug delivery

  • GPC/SEC molecular weight & polydispersity analysis
  • NMR block-length determination
  • FTIR structural verification
  • DSC/TGA thermal analysis
04

Mass Spectrometry Based Analytical Services

  • Nitrosamine Testing & Regulatory Compliance
  • Extractables & Leachables (E&L) Testing
  • High-Resolution Mass Spectrometry & Structural Elucidation
  • Gas Chromatography Mass Spectrometry (GCMS) Analysis
  • Impurity Identification and Characterization

About ResolveMass Laboratories

We take on the molecules other labs hand back.

ResolveMass is a Canadian CRO and CDMO built around one idea: complex pharmaceutical projects — peptides, engineered polymers, controlled-release systems — need one team that can carry them from synthesis to submission, not four vendors that each own a piece of the problem.

4 disciplines under one roof — synthesis, formulation, polymer science, mass spec
9+ countries served, from a single site in Laval, Québec
3 regulatory certifications held — Health Canada GMP, FDA registration, ISO 9001:2015
Compliance

GMP-compliant under Health Canada. FDA-registered. ISO 9001:2015 certified.

Health Canada
GMP Compliant
Drug Establishment Licence holder
FDA Registration
Establishment ID
3042696771
Quality System
ISO 9001:2015
Certified
Headquarters
Laval, Québec
500 Bd Cartier O, H7V 5B7
Why we started
“We built the lab we wished we’d had — one place where a difficult molecule doesn’t have to change hands four times to get an answer.”

ResolveMass Laboratories was founded in Laval, Québec, by chemists and analytical scientists who spent their careers on the harder end of drug development — peptide-oligonucleotide conjugates, novel polymer architectures, controlled-release formulations. That kind of work tends to stall inside labs built for routine small-molecule projects, passed between separate synthesis, analytical, and formulation vendors that don’t share context.

So we set up ResolveMass differently: custom synthesis, formulation development, polymer science, and mass spectrometry sit inside one team, working from the same data. It’s a structure built for the questions our clients actually bring us, not for a standard workflow they have to fit into.

Mission

Deliver top-tier contract research and development across complex drug development, polymer synthesis, and analytical chemistry — so our partners can move a breakthrough from bench to patient.

Vision

Set the standard for how complex, novel drug-delivery projects get developed: precise, transparent, and built around the molecule — not around a standard workflow.

One team, four disciplines

Most projects touch more than one of these — that’s the point. Nothing here is handed off to a separate vendor.

DISC

Drug Discovery & Generic Development

  • Formulation & analytical development, novel and generic
  • Regulatory support for IND and ANDA projects
  • Peptide programs — semaglutide, liraglutide, tirzepatide, lanreotide, nusinersen
SYN

Custom Synthesis

  • Custom API and intermediate synthesis
  • Forced-degradation impurity synthesis
  • Peptide-oligonucleotide conjugation (POCs)
POLY

Polymer Science

  • PLGA, PLA, PCL, PEG-copolymers & novel architectures
  • Molecular weight & polydispersity analysis
  • NMR, FTIR, DSC/TGA characterization
MS

Mass Spectrometry & Analytics

  • HRMS exact-mass & structural elucidation
  • Bioanalytical, biomarker, proteomic, lipidomic & metabolomic services
  • Signature testing lines below — peptide, nitrosamine & E&L
Signature Analytical Services

Where clients bring us the hardest questions

These three lines account for most of what lands on our bench first — the testing that’s hardest to source elsewhere.

LC-MS · HRMS · Peptide Mapping

Peptide Characterization

Sequence verification, modification detection, and stability-indicating methods for GLP-1s and other complex peptide APIs.

  • Structural confirmation & sequence mapping
  • Oxidation, deamidation, truncation & aggregate ID
  • Forced degradation & batch-to-batch consistency
Data aligned with FDA & ICH guidance
LC-MS/MS · GC-MS

Nitrosamine Testing

Trace-level detection of nitrosamine drug substance-related impurities (NDSRIs), with risk assessment built into the same engagement.

  • Chemical & structural risk assessment
  • Screening & control method development
  • Batch-to-batch monitoring & filing support
Per FDA guidance on nitrosamine impurities in human drugs
GC-MS · LC-MS · ICP-MS · IC · NMR

Extractables & Leachables

Full E&L programs across packaging, delivery systems, and manufacturing contact materials — from risk assessment to safety qualification.

  • Systematic extractables studies, multi-solvent & thermal
  • Leachables monitoring, accelerated & real-time
  • Toxicological risk assessment & reporting
USP <1663>/<1664> · ICH Q3D · ISO 10993

What that structure gets you

No context lost between vendors

Synthesis, formulation, polymer science, and mass spec run from the same lab and the same dataset — nothing gets re-explained to a new contractor mid-project.

Built for the difficult cases

Peptide conjugates, engineered polymers, and controlled-release systems are the daily work here, not an exception request.

PhD scientists on the bench

Projects are run by the chemists and analytical scientists doing the work, not relayed through account managers.

Canadian-based, globally qualified

GMP-compliant under Health Canada, FDA-registered, and ISO 9001:2015 certified — the regulatory bar our clients need wherever they file.

One lab. Global reach. Every project under NDA.

Every engagement is confidential by default — that’s also why you won’t find client logos on this page. What we can show you is where the work goes:

CANADA UNITED STATES FRANCE UNITED KINGDOM GERMANY JAPAN SOUTH KOREA AUSTRALIA INDIA

Have a molecule that needs more than a standard workflow?

Book a call with our scientific team and walk through the project directly with the chemists who’d run it.

Book a Meeting
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