Introduction: Deuterated Acrylamide’s Expanding Role in Modern Science
Deuterated Acrylamide and its analogs have gained substantial importance in fields such as NMR spectroscopy, polymer science, and pharmaceutical R&D. These isotopically labeled compounds, including Deuterated N-Isopropyl acrylamide-d3, d7, and d10, allow researchers to explore molecular behavior and interactions with high precision. By replacing hydrogen with deuterium, scientists can obtain clearer NMR data and more predictable polymer behavior, essential for high-resolution research environments.
At ResolveMass Laboratories, we offer a comprehensive selection of deuterated acrylamide derivatives ranging from d3 to d12. These variants are manufactured under stringent quality control, ensuring they meet the highest purity standards for sensitive applications.
Explore the science further in our Comprehensive Guide to Deuterated Polymers.
Why Deuterated Acrylamide Matters in Precision Research
The strategic use of deuterium in acrylamide compounds leads to significant advantages. Deuterium alters both the kinetic properties and NMR signal profiles, which enhances the reliability of experimental results. These compounds improve spectral resolution, reduce background noise, and offer superior stability in thermal and chemical environments.
As a result, Deuterated Acrylamide variants are invaluable for studies involving structural characterization, polymer chain dynamics, and biological molecule interactions under various stimuli.
Our Portfolio: High-Purity Deuterated Acrylamide Variants
ResolveMass Laboratories specializes in synthesizing highly pure, isotopically enriched acrylamide derivatives to meet diverse research demands.
Deuterated N-Isopropyl Acrylamide-d3
This variant is ideal for studies requiring selective deuteration. Deuterated N-Isopropyl acrylamide-d3 is particularly suited for localized NMR environments where specific proton suppression enhances structural analysis and protein interactions.
Deuterated N-Isopropyl-d7 Acrylamide
Engineered for more profound isotope effects, Deuterated N-Isopropyl-d7 acrylamide supports dynamic NMR investigations and polymer transition studies. It is frequently used to examine polymer flexibility and conformational changes in solution.
Deuterated N-Isopropyl Acrylamide-d10
With ten deuterium atoms, Deuterated N-Isopropyl acrylamide-d10 delivers maximum proton suppression. It’s an excellent choice for smart hydrogel systems, protein-polymer conjugates, and thermoresponsive formulations. Its high isotope content allows reproducible results in highly sensitive biological systems.
Explore the science further in our Comprehensive Guide to Deuterated Polymers.
Case Study: Thermo-Sensitive Hydrogel Monitoring Using Acrylamide-d10
Client: University Polymer Chemistry Department (2024)
Objective: Investigate LCST behavior in thermoresponsive hydrogels using Deuterated N-Isopropyl acrylamide-d10.
Methodology
- Synthesized 50g of acrylamide-d10 (>98% isotopic purity)
- Integrated into a poly(NIPAAm) hydrogel matrix
- Performed NMR analysis (600 MHz) across 25–35°C to detect phase transition behavior
Results
- Signal-to-noise ratio increased by 3.4x due to efficient proton suppression
- Consistent thermal response observed across multiple NMR cycles
- Findings published in Journal of Polymer Science, April 2024
Why Choose ResolveMass for Deuterated Acrylamide Solutions?
ResolveMass Laboratories delivers more than just chemical compounds—we offer complete support for your research objectives. Whether your work involves macromolecular NMR, drug delivery systems, or functional polymer materials, our expertise ensures reliable, reproducible results.
Our Key Differentiators:
- Rigorous quality control via NMR, HPLC, and MS analysis
- Deuterium enrichment consistently above 98%
- Support for R&D-scale to industrial-scale quantities
- Custom labeling strategies and flexible timelines
- CRO support from synthesis through data interpretation
FAQs: Deuterated Acrylamide Applications and Ordering
They suppress proton interference, enhancing clarity in molecular and polymer NMR studies.
d3 offers limited deuteration suitable for localized analysis, whereas d10 provides maximum suppression for full-spectrum kinetic studies.
Yes, they retain polymerizable acrylamide groups compatible with radical and photo-polymerization techniques.
Absolutely. We offer d4, d8, d12 variants and more based on your labeling and application needs.
Yes, we support orders ranging from milligrams to kilograms for both academia and industry.
Depending on complexity, custom projects usually take 2–5 weeks. We provide regular progress updates.
Just visit our contact page or request a quote through the Custom Synthesis CRO page.
Conclusion: Empowering Research with Deuterated Acrylamide
In today’s precision-driven research landscape, Deuterated Acrylamide compounds are essential for molecular insight and reproducibility. Whether you’re exploring drug-polymer interactions, phase transitions, or structural mapping, our isotopically labeled acrylamides—like Deuterated N-Isopropyl acrylamide-d3, d7, and d10—are trusted by scientists worldwide.
With decades of experience and a focus on quality, ResolveMass Laboratories is your reliable partner in next-generation chemical research.
🧪 Need assistance with your next experiment? Contact ResolveMass Labs today.
