PLGA (Poly(lactic-co-glycolic acid)

PLGA (Poly(lactic-co-glycolic acid)) is a biodegradable and biocompatible copolymer composed of lactic acid (LA) and glycolic acid (GA) monomers. Due to its tunable degradation rate, biocompatibility, and excellent mechanical properties, PLGA has become a gold standard in pharmaceutical research, drug delivery systems, and tissue engineering applications.

At ResolveMass Laboratories Inc., we provide a wide range of PLGA polymers with varied lactic-to-glycolic acid ratios (e.g., 50:50, 75:25, 85:15), molecular weights, and end-group functionalities (acid- or ester-terminated). This flexibility allows researchers to customize drug release profiles, optimize nanoparticle formulations, and engineer biodegradable scaffolds for advanced biomedical applications.

PLGA is extensively used for:

  • Sustained and controlled drug delivery: Microspheres, nanoparticles, and implants for small molecules, peptides, and proteins.

  • Tissue engineering and regenerative medicine: Biodegradable scaffolds that support cell growth and tissue regeneration.

  • Biomedical device coating: Temporary coatings to modulate drug release or protect devices from biofouling.

  • Pharmaceutical formulation research: Preclinical studies requiring reproducible polymer characteristics.

Each batch of PLGA from ResolveMass is carefully synthesized and characterized using GPC, NMR, and HPLC to ensure consistent molecular weight, monomer ratio, and purity. We also offer custom PLGA synthesis and polymer modifications, enabling researchers to tailor polymers for specific drug delivery and biomedical applications.

With our high-quality PLGA products, scientists and formulation developers can achieve precise control over degradation rates, mechanical properties, and drug release kinetics, making PLGA an indispensable tool in advanced pharmaceutical and biomedical research.

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