Poly(caprolactone) (PCL)

Poly(caprolactone) (PCL) is a biodegradable, biocompatible, and semicrystalline aliphatic polyester widely used in drug delivery, tissue engineering, and biomedical research. Known for its low melting point, flexibility, and slow degradation rate, PCL offers versatile applications in controlled release systems, polymer blends, and scaffold fabrication.

At ResolveMass Laboratories Inc., we provide high-quality PCL polymers with varied molecular weights (7k–240k Da), customizable end-groups, and precise polymer specifications to meet the diverse needs of pharmaceutical and biomedical researchers. This allows for tailored mechanical properties, degradation rates, and formulation compatibility for specific applications.

Key applications of PCL include:

  • Sustained and controlled drug delivery: PCL-based microspheres, nanoparticles, and implants for small molecules, peptides, and proteins.

  • Tissue engineering and regenerative medicine: Biodegradable scaffolds and matrices supporting cell growth and tissue regeneration.

  • Polymer blending and copolymer synthesis: Combining PCL with other biodegradable polymers like PLGA to modulate properties such as degradation rate and mechanical strength.

  • Medical device coatings and implants: Flexible, biocompatible coatings for biomedical devices and controlled release implants.

All PCL products from ResolveMass are manufactured and characterized to ensure reproducibility and consistent quality. Characterization methods include GPC, NMR, and thermal analysis, confirming molecular weight, polydispersity, and purity. Our high-quality PCL products are suitable for research, preclinical studies, and custom formulation development, providing scientists with reliable materials for innovative biomedical applications.

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