1,2-Propanediamine-d3 | CAS 2708283-46-7

OVERVIEW  of  1,2-Propanediamine-d3 | CAS 2708283-46-7

1,2-Propanediamine-d₃ (CAS 2708283-46-7) is a deuterium-labeled analog of 1,2-propanediamine, in which three hydrogen atoms are replaced by deuterium. This compound serves as a valuable stable isotope-labeled reagent for use in NMR spectroscopy, mass spectrometry, and mechanistic chemistry studies. It enables researchers to trace chemical pathways and analyze molecular interactions without interference from native hydrogen signals.

CHEMICAL INFORMATION

• Name: 1,2-Propanediamine-d₃

• Molecular Formula: C₃H₇D₃N₂

• Molecular Weight: 77.15 g/mol

• CAS Number: 2708283-46-7

• Isotopic Enrichment: ≥ 98 atom % D

• Chemical Class: Deuterated aliphatic diamine

• Solubility: Miscible with water, alcohols, and most polar solvents

APPLICATIONS  of  1,2-Propanediamine-d3 | CAS 2708283-46-7

• Mass Spectrometry (MS):
  Serves as an internal standard or reference compound for quantifying amine-containing molecules. The deuterium label allows clear mass separation from unlabeled analogs.

• NMR Spectroscopy:
  Useful for signal suppression and structural elucidation of related compounds. Deuterium labeling reduces proton interference and enhances spectral resolution.

• Isotope Tracing Studies:
  Used in metabolic and mechanistic investigations to study the behavior, transformation, and incorporation of diamines in chemical or biological systems.

• Synthetic Intermediate:
  Acts as a deuterated building block for the synthesis of labeled pharmaceuticals, coordination complexes, and polymers requiring isotopic labeling.

ADVANTAGES  of  1,2-Propanediamine-d3 | CAS 2708283-46-7

• High isotopic purity (≥98 atom % D).

• Chemically and thermally stable.

• Compatible with aqueous and organic analytical systems.

• Provides accurate isotope tracing in quantitative assays.

• Facilitates mechanistic and kinetic investigations.

HANDLING AND SAFETY

• Handling: Avoid inhalation and direct contact; use in a well-ventilated area.

• Protective Equipment: Laboratory gloves, safety goggles, and protective clothing recommended.

• Storage: Keep in airtight containers under inert gas; protect from moisture.

• Stability: Stable under normal laboratory conditions.

• Disposal: Dispose of in accordance with local regulations and safety protocols for amine compounds.

SUMMARY
1,2-Propanediamine-d₃ (CAS 2708283-46-7) is a deuterium-enriched aliphatic diamine widely used as an analytical standard, tracer, and synthetic intermediate. Its stability, isotopic purity, and compatibility with various analytical techniques make it ideal for quantitative isotope studies, reaction mechanism analysis, and NMR/MS applications in both chemical and biochemical research.