PRODUCT NAME
Deuterated 1,3,5-Trimethyl-1,3,5-triethyl-d₆ Cyclotrisiloxane
CAS NUMBER
15901-49-2
OVERVIEW
1,3,5-Trimethyl-1,3,5-triethyl-d6 cyclotrisiloxane | CAS 15901-49-2 is a high-purity, isotopically labeled cyclotrisiloxane designed specifically for analytical, research, and calibration applications. With six strategically incorporated deuterium atoms, this compound serves as an indispensable reference standard or internal standard in advanced mass spectrometry methodologies. The deuterium labeling enables excellent resolution from non-labeled analogs while preserving the chemical behavior and volatility required for reliable analytical performance.
This specialized organosilicon compound is commonly used in GC/MS calibration, method development, and quantitative analysis of siloxane contaminants or cyclic siloxane compounds in environmental and industrial samples. Its isotopic signature makes it uniquely valuable in laboratories where analytical precision, reproducibility, and trace-level detection are critical.
CHEMICAL IDENTITY
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Chemical Name: 1,3,5-Trimethyl-1,3,5-triethyl-d₆ Cyclotrisiloxane
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CAS Registry Number: 15901-49-2
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Molecular Formula: C₉H₁₈D₆O₃Si₃
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Exact Mass: Dependent on isotopic composition (enriched with deuterium)
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Synonyms: d₆ Cyclotrisiloxane, Deuterated D3 Siloxane, Deuterium-Labeled Cyclotrisiloxane
KEY APPLICATIONS of 1,3,5-Trimethyl-1,3,5-triethyl-d6 cyclotrisiloxane | CAS 15901-49-2
Internal and Surrogate Standard in Mass Spectrometry
The deuterium incorporation shifts the mass spectrum in a predictable way, allowing this compound to act as an internal standard in GC/MS and LC/MS analyses without co-eluting with the unlabeled target analytes. This improves quantification accuracy, especially for trace-level detection.
Calibration & System Suitability Testing
Used for regular calibration of analytical instruments, particularly in environmental monitoring labs tracking siloxane pollutants or in semiconductor manufacturing analytics where cyclic siloxanes appear in process gases or waste streams.
Method Development & Validation
Ideal for developing robust analytical protocols for cyclic siloxanes, siloxane degradation products, or siloxane-related impurities. Its deuterated analog provides a reliable benchmark for assessing extraction efficiency, matrix effects, and instrument response reproducibility.
Research-Level Investigations
Used in polymer research and organosilicon chemistry studies to better understand reaction mechanisms, isotopic effects, and degradation pathways. Deuterium labeling assists in tracking molecular transformations via NMR and MS techniques.
ANALYTICAL BENEFITS OF DEUTERIUM LABELING
Enhanced Mass Spectrometry Performance
Deuterated standards simplify data interpretation by producing distinctive peaks separated by known mass differences from corresponding non-labeled compounds. This differentiation improves peak identification and quantitation precision.
Minimal Chemical Perturbation
Because deuterium is chemically similar to protium (¹H), labeled compounds retain virtually identical retention times to non-labeled analogs in GC and LC methods. This allows for accurate internal standards without drastically altering chromatographic behavior.
Reduced Matrix Interference
In complex sample matrices (e.g., wastewater, soil extracts, manufacturing effluents), using a labeled internal standard can compensate for signal suppression or enhancement, leading to more reliable quantitative results.
QUALITY ASSURANCE
At ResolveMass Laboratories Inc., we ensure every batch of Deuterated 1,3,5-Trimethyl-1,3,5-triethyl-d₆ Cyclotrisiloxane undergoes rigorous quality control, including:
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Purity Verification: Verified by GC/MS and/or NMR to confirm isotopic enrichment and chemical integrity
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Certificate of Analysis: Provided with every shipment, detailing lot-specific analytical results
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Traceability: Each batch is fully traceable from synthesis through final packaging
WHY CHOOSE RESOLVEMASS?
ResolveMass Laboratories Inc. is committed to supplying high-performance isotopically labeled compounds that meet the exacting demands of analytical chemists and researchers worldwide. Our products are backed by expert technical support, reliable delivery, and uncompromising quality.
Whether you’re standardizing your mass spectrometer, validating new methods, or conducting pioneering research, our Deuterated 1,3,5-Trimethyl-1,3,5-triethyl-d₆ Cyclotrisiloxane provides the accuracy and consistency you depend on.
Learn more about Deuterated Chemicals,
- Deuterated Polymers: A Cornerstone Guide to Synthesis, Applications, and Future Trends
- Availability of All the Deuterated Chemicals at ResolveMass Laboratories Inc.
- ResolveMass Laboratories: Leading Deuterated Chemical Synthesis Company in the United States.
- Deuterated Internal Standards for LC-MS: Selection & Custom Synthesis
- How to Choose the Right Deuterated Labelled Chemical Synthesis Company in Canada
- How to Choose the Right Deuterium Labelled Compounds Supplier for Your Lab
- Deuterium-Labelled Compounds — Synthesis, Applications & Ordering
- Custom Synthesis of Deuterated Chemicals
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