Deuterated 4-Hydroxystyrene-α,β,β-d3 | CAS 2628-17-3

PRODUCT OVERVIEW

Deuterated 4-Hydroxystyrene-α,β,β-d3 | CAS 2628-17-3  is a high-purity isotopically labeled organic compound designed for advanced research, analytical reference standards, and specialized synthesis applications. In this molecule, three hydrogen atoms located at the α and β positions relative to the vinyl group have been selectively replaced with deuterium — the stable heavy isotope of hydrogen. This strategic labeling provides distinct spectroscopic signatures that support precise qualitative and quantitative analysis in nuclear magnetic resonance (NMR), mass spectrometry (MS), and other tracer-based analytical techniques.

The deuterium substitution increases molecular mass in a predictable way without significantly altering the chemical structure or reactivity of the base molecule. As such, Deuterated 4-Hydroxystyrene-α,β,β-d3 serves as an indispensable tool in research areas including mechanistic studies, metabolic tracing, and calibration of analytical instrumentation.

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CHEMICAL INFORMATION

• Chemical Name: Deuterated 4-Hydroxystyrene-α,β,β-d3

• CAS Number: 2628-17-3

• Molecular Formula: C8H5D3O

• Isotopic Labeling: Deuterium substitution at α, β, β positions

• Molecular Weight: 123.17 g/mol

• Synonyms: 4-Hydroxystyrene-d3 (specific labeled positions), 4-Vinylphenol-d3

This compound is a derivative of the well-known aromatic building block 4-hydroxystyrene, with isotopic modification for use in specialized analytical applications.

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KEY FEATURES & BENEFITS

High Isotopic Purity
ResolveMass Laboratories ensures rigorous control over deuterium incorporation. High isotopic enrichment yields clear, interpretable analytical data and minimizes spectral overlap from protium (¹H) signals in deuterium-sensitive detection methods.

Analytical Reliability
Deuterated compounds such as this one are widely employed as internal standards in quantitative mass spectrometry assays due to consistent mass differences from non-labeled analytes. This facilitates accurate quantitation in complex sample matrices.

NMR Performance
The specific deuterium labeling significantly reduces proton signals at the labeled positions in ¹H NMR spectra, simplifying spectral interpretation and enhancing resolution of neighboring resonances. This makes the product ideal for structural confirmation, peak assignment, and kinetic studies.

Versatile Research Applications
Whether used as a tracer for reaction pathways, metabolic studies, or as a standard for instrument calibration, Deuterated 4-Hydroxystyrene-α,β,β-d3 supports a broad range of scientific investigations in academic, pharmaceutical, and industrial laboratories.

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APPLICATIONS  of  Deuterated 4-Hydroxystyrene-α,β,β-d3 | CAS 2628-17-3

 

Analytical Standardization

• Internal standard for LC-MS and GC-MS quantitation
• Reference for calibration curves in method validation
• Matrix spike for recovery studies

Spectroscopic Investigation

• Reduced signal interference in ¹H NMR experiments
• Deuterium-based relaxation studies
• Structural elucidation via isotopic shifts

Mechanistic & Metabolic Tracing

• Tracing reaction pathways in synthetic chemistry
• Probing metabolic transformations in biological systems
• Distinguishing labeled vs. unlabeled pathways in enzyme kinetics

Method Development

• Supporting high-throughput assay optimization
• Evaluation of instrument performance over time
• Cross-laboratory analytical standard comparisons

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PHYSICAL & SPECTRAL CHARACTERISTICS

Deuterium incorporation affects the vibrational frequencies and NMR behavior relative to non-labeled analogues. Representative spectral data may include:

• ¹H NMR: Simplified spectrum at labeled positions due to replacement by deuterium.

• Mass Spectrometry: Molecular ion shifts corresponding to +3 atomic mass units compared to 4-Hydroxystyrene.

• Other Spectroscopy: Deuterium substitution can induce predictable shifts in IR and Raman active modes.

Precise spectral data will be provided with the product certificate to aid in compound verification and analytical assignment.

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QUALITY ASSURANCE

Each batch is subjected to rigorous quality control protocols, including but not limited to:

• Verification of isotopic purity via NMR or MS

• Structural confirmation

• Purity assessment against established chemical standards

• Documentation in a certificate of analysis (COA)

ResolveMass Laboratories adheres to stringent production and quality management practices to ensure product consistency and research confidence.

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ORDERING INFORMATION

ResolveMass Laboratories offers this product in multiple size options to accommodate varying research needs. Custom isotopic specifications may be available on request.

For pricing, lead times, and technical queries, contact our scientific support team or visit the product page on resolvemass.ca.

 

Learn more about Deuterated Chemicals through,

• Deuterated Polymers: A Cornerstone Guide to Synthesis, Applications, and Future Trends
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• ResolveMass Laboratories: Leading Deuterated Chemical Synthesis Company in the United States.
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• How to Choose the Right Deuterated Labelled Chemical Synthesis Company in Canada 
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