OVERVIEW
Deuterated Ethyl-d5 methacrylate | CAS 55935-46-1 is a high-purity, isotopically labeled monomer designed for advanced analytical, polymer research, and mechanistic studies. Structurally analogous to standard ethyl methacrylate but containing five deuterium atoms, this molecule offers enhanced spectral clarity and tracer capabilities across NMR, MS, polymerization tracking, and reaction-pathway investigations. Its stability, compatibility with radical polymerization systems, and clean isotopic signature make it a valuable reagent in academic, pharmaceutical, and materials-science environments.
As a specialty deuterated methacrylate, it is frequently used to synthesize labeled polymers, investigate degradation pathways, quantify copolymer compositions, monitor polymer chain mobility, and perform structural studies with minimal background interference. ResolveMass Laboratories Inc. supports researchers with materials optimized for reproducibility, analytical rigor, and demanding experimental use cases.
CHEMICAL INFORMATION
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Chemical Name: Deuterated Ethyl-d5 Methacrylate
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CAS Number: 55935-46-1
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Molecular Formula: C6D5H5O2
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Synonyms: Ethyl Methacrylate-d5, Ethyl 2-methyl-2-propenoate-d5
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Molecular Class: Deuterated methacrylate ester
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Functional Groups: Methacrylate ester, deuterated ethyl group
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General Appearance: Clear, colorless liquid
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Stability: Stable under recommended storage conditions; sensitive to polymerization when exposed to heat, light, or radical initiators
This isotopically labeled monomer retains the reactive vinyl functionality for polymerization, making it chemically comparable to conventional ethyl methacrylate while providing isotopic differentiation through deuterium labeling.
KEY FEATURES & BENEFITS
1. High Deuterium Incorporation
With five deuterium atoms replacing protium in the ethyl group, the compound provides a distinct isotopic signature ideal for tracing and differentiation in complex systems.
2. Enhanced Spectral Clarity
Deuteration reduces proton-related spectral noise, improving accuracy in NMR and MS-based studies. This allows researchers to track polymer structure, dynamics, and monomer reactivity with greater precision.
3. Excellent Compatibility with Polymerization Systems
The methacrylate double bond readily participates in free-radical polymerizations, enabling the synthesis of labeled homopolymers, copolymers, and block polymers.
4. Ideal for Mechanistic Research
The isotopic label supports in-depth study of chain-transfer behavior, degradation kinetics, radical propagation, and structural rearrangements.
5. Suitable for Quantitative and Qualitative Analysis
It enhances analytical differentiation in mixed systems, aiding in copolymer ratio measurement, molecular mobility assessment, and degradation product identification.
APPLICATIONS of Deuterated Ethyl-d5 methacrylate | CAS 55935-46-1
1. Polymer Science & Materials Research
Deuterated Ethyl-d5 Methacrylate is widely used to create isotopically labeled methacrylate polymers. These polymers are valuable for studying:
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Polymer chain dynamics via NMR relaxation
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Segmental mobility in block copolymers
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Interfacial phenomena in polymer blends
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Degradation pathways and lifetime prediction
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Copolymer composition during complex syntheses
Using a labeled monomer allows selective observation of specific polymer segments without background interference.
2. NMR Spectroscopy & Structural Elucidation
Its deuterium content minimizes proton signals, enhancing resolution and enabling:
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Selective tracking of monomer incorporation
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Polymer microstructure analysis
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Reaction monitoring with reduced spectral complexity
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Precise quantification of isotopic distributions
This makes the compound indispensable for high-precision NMR studies.
3. Mass Spectrometry (MS) Tracing
The isotopic shift from deuterium improves detection and quantification in MS workflows such as:
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Tracking polymer degradation fragments
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Studying reaction intermediates
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Monitoring monomer consumption in real time
4. Kinetic and Mechanistic Investigations
Because deuterium-labeled compounds alter bond-vibrational properties, they help researchers explore:
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Kinetic isotope effects
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Radical propagation behavior
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Competitive copolymerization mechanisms
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Side-reaction pathways
5. Analytical Standards and Method Development
Deuterated monomers are frequently used as internal standards and calibration materials for developing and validating analytical methods in polymer characterization.
WHY CHOOSE RESOLVEMASS LABORATORIES INC.
ResolveMass Laboratories Inc. provides high-purity deuterated chemicals tailored for advanced scientific workflows. Our rigorous quality-control standards ensure each batch meets analytical, structural, and isotopic specifications suitable for demanding R&D programs. Researchers trust ResolveMass for reliability, reproducibility, and expert-grade materials that support breakthroughs in polymer science, analytical chemistry, and materials engineering.
Learn more through,
Deuterated Polymers: A Cornerstone Guide to Synthesis, Applications, and Future Trends
Availability of All the Deuterated Chemicals at ResolveMass Laboratories Inc.
ResolveMass Laboratories: Leading Deuterated Chemical Synthesis Company in the United States.
Deuterated Internal Standards for LC-MS: Selection & Custom Synthesis
How to Choose the Right Deuterated Labelled Chemical Synthesis Company in Canada
How to Choose the Right Deuterium Labelled Compounds Supplier for Your Lab
Deuterium-Labelled Compounds — Synthesis, Applications & Ordering
Custom Synthesis of Deuterated Chemicals





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