Deuterated Isoprene-d7

OVERVIEW
Deuterated Isoprene-d7 is a stable-isotope-labeled analog of isoprene in which seven hydrogen atoms are replaced with deuterium. This high-purity, non-radioactive compound is widely used in advanced analytical chemistry, polymer science, reaction mechanism studies, and metabolic research. Its unique isotopic labeling makes it a powerful internal standard and a valuable molecular tracer in spectroscopic and kinetic investigations. At ResolveMass Laboratories Inc., Deuterated Isoprene-d7 is supplied with exceptional chemical purity and isotopic enrichment, supporting reliable and reproducible results across a wide range of technical and scientific applications.

As the simplest conjugated diene and a precursor to many synthetic elastomers, isoprene and its labeled derivatives play a central role in materials research, environmental chemistry, and biosynthetic pathway elucidation. Isoprene-d7 enables precise tracking of molecular transformations by shifting spectral signatures in NMR, MS, and IR analyses. Its deuterium substitution results in mass and vibrational differences without significantly altering the compound’s fundamental reactivity. This makes Deuterated Isoprene-d7 particularly valuable for mechanistic studies where isotopic effects can be measured and interpreted to understand reaction pathways more deeply.

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CHEMICAL INFORMATION
• Chemical Name: Isoprene-d7
• Synonyms: 2-Methyl-1,3-butadiene-d7, Deuterated Isoprene
• Molecular Formula: C5D7 
• Isotopic Enrichment: High deuterium incorporation (commonly ≥98 atom % D)
• Molecular Weight: 75.16 g/mol

The incorporation of seven deuterium atoms alters the compound’s mass, IR vibrational frequencies, and NMR spectra without drastically changing its chemical behavior. This combination of chemical similarity and spectroscopic distinctness is precisely why Deuterated Isoprene-d7 is such a versatile research tool.

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KEY FEATURES
• High isotopic enrichment suitable for quantitative MS and NMR
• Structural and chemical behavior closely parallels native isoprene
• Ideal internal standard for trace-level quantification
• Useful for polymerization mechanism studies and kinetic isotope effect analysis
• Compatible with advanced analytical workflows including GC-MS, LC-MS, and 1H/2H NMR
• Produced with strict quality control to ensure purity, consistency, and stability

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APPLICATIONS

1. Analytical Chemistry and Stable Isotope Tracing
Deuterated Isoprene-d7 provides clean, predictable mass shifts that make it an exceptional internal standard in GC-MS and LC-MS. Its isotopic label allows researchers to distinguish between endogenous or sample-derived isoprene and the spiked standard. This is highly beneficial in quantitative analysis, metabolic profiling, environmental VOC studies, and biomarker research.

2. Polymerization and Mechanistic Chemistry
Because isoprene is a central monomer in synthetic rubbers, isotopically labeled isoprene is widely used to investigate polymer formation mechanisms. Deuterated Isoprene-d7 helps researchers monitor chain propagation, radical intermediates, and rearrangement pathways. It is also valuable in kinetic isotope effect (KIE) studies that provide insight into bond-breaking and formation steps during polymerization.

3. Spectroscopic Method Development
The deuterium substitution provides distinct NMR signatures (1H disappearance and 2H signals) and shifted vibrational frequencies in IR/Raman spectroscopy. This offers clean spectral separation and enables validation of instrument performance, calibration of analytical methods, and differentiation of molecule fragments in high-resolution mass spectrometry.

4. Environmental and Atmospheric Research
Isoprene plays an important role in atmospheric chemistry and is one of the most abundant volatile organic compounds (VOCs) emitted by plants. Deuterated Isoprene-d7 allows researchers to track oxidation pathways, reaction rates with radicals, and formation of secondary organic aerosols. The isotopic label makes it easier to distinguish synthetic tracers from natural background emissions.

5. Biosynthetic and Metabolic Studies
In life sciences, Deuterated Isoprene-d7 is used to probe metabolic pathways related to isoprenoid biosynthesis, lipid formation, and cellular VOC production. Tracking deuterium incorporation helps map metabolic flux, identify intermediates, and investigate enzyme-specific transformations.

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ADVANTAGES FOR RESEARCH AND INDUSTRY
• High analytical precision: Enables accurate isotope-dilution quantification.
• Excellent traceability: Clear mass separation from native isoprene simplifies interpretation.
• Stable and reliable: Deuterium label remains intact under typical analytical conditions.
• Supports complex workflows: Compatible with polymer science, mechanistic chemistry, environmental monitoring, and metabolomics.
• Improved method robustness: Facilitates calibration, method validation, and control studies.

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QUALITY & COMPLIANCE
ResolveMass Laboratories Inc. ensures that every batch of Deuterated Isoprene-d7 undergoes rigorous quality checks, including purity assessment, isotopic enrichment verification, and stability confirmation. All products are manufactured following strict laboratory standards to support consistency, reproducibility, and regulatory compliance for research applications.

 

Learn more through,

Deuterated Polymers: A Cornerstone Guide to Synthesis, Applications, and Future Trends

Availability of All the Deuterated Chemicals at ResolveMass Laboratories Inc. 

ResolveMass Laboratories: Leading Deuterated Chemical Synthesis Company in the United States. 

Deuterated Internal Standards for LC-MS: Selection & Custom Synthesis 

How to Choose the Right Deuterated Labelled Chemical Synthesis Company in Canada 

How to Choose the Right Deuterium Labelled Compounds Supplier for Your Lab 

Deuterium-Labelled Compounds — Synthesis, Applications & Ordering 

Custom Synthesis of Deuterated Chemicals