Di-n-propyl Phthalate-3,4,5,6-d4 | CAS 358731-29-0

OVERVIEW  of  Di-n-propyl Phthalate-3,4,5,6-d4

Di-n-propyl phthalate-3,4,5,6-d₄ (CAS 358731-29-0) is a stable isotope–labeled phthalate ester widely used as an internal standard for highly accurate quantification of di-n-propyl phthalate (DnPP). The presence of four deuterium atoms in the aromatic ring ensures a distinct mass shift, allowing precise isotope-dilution mass spectrometric analysis.

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CHEMICAL INFORMATION

• Name: Di-n-propyl phthalate-d₄

• Molecular Formula: C₁₄H₁₄D₄O₄

• Molecular Weight: ~254.32  g/mol

• CAS Number: 358731-29-0

• Isotopic Enrichment: ≥ 98% D (typical)

• Chemical Class: Deuterated phthalate ester

• Solubility: Soluble in most organic solvents; negligible in water

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APPLICATIONS  of  Di-n-propyl Phthalate-3,4,5,6-d4 | CAS 358731-29-0

• Isotope-Dilution Internal Standard for GC-MS or LC-MS quantification of DnPP in environmental, food-contact, and industrial samples.

• Environmental Monitoring of phthalate contamination in soil, water, air, and sediments.

• Toxicological and Exposure Studies involving human or animal samples.

• Quality Control & Method Validation for calibration curve preparation, spike recovery, extraction efficiency, and analytical reproducibility.

• Material Migration Studies of phthalate release from plastics, polymers, adhesives, PVC materials, etc.

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ADVANTAGES  of  Di-n-propyl Phthalate-3,4,5,6-d4 | CAS 358731-29-0

• High Analytical Accuracy: Deuterium label provides a precise mass shift, improving calibration and reducing matrix effects.

• Enhanced Reproducibility: Ideal for consistent results across multiple analytical runs.

• Strong Structural Similarity: Chemically identical to native DnPP, ensuring matching extraction and ionization behavior.

• Improved Detection Sensitivity: Boosts sensitivity in trace-level quantification using GC-MS or LC-MS.

• Reliable Standard for Regulatory Testing: Suitable for phthalate compliance monitoring in consumer products and environmental samples.

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SUMMARY
Di-n-propyl phthalate-3,4,5,6-d₄ is a high-purity deuterated internal standard designed for precise detection and quantification of DnPP using mass spectrometry. Its isotopic labeling ensures excellent analytical performance, making it indispensable for environmental surveillance, industrial QC testing, toxicology studies, and regulatory compliance workflows.

 

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