n-Pentyl-2,2,3,3,4,4,5,5,5-d9 Alcohol | CAS 148587-12-6

OVERVIEW  of  n-Pentyl-2,2,3,3,4,4,5,5,5-d9 Alcohol | CAS 148587-12-6

n-Pentyl-2,2,3,3,4,4,5,5,5-d₉ alcohol (CAS 148587-12-6) is a deuterium-labeled analog of n-pentanol, containing nine deuterium atoms strategically incorporated along the carbon chain. This fully characterized isotopologue is widely used in mass spectrometry, environmental analysis, metabolic research, and method development where precise isotope dilution quantification is required. Because it mirrors the chemical properties of native n-pentanol, it provides accurate internal standardization and method calibration across a variety of analytical platforms.

CHEMICAL INFORMATION

• Name: n-Pentyl-d₉ alcohol

• Molecular Formula: C₅D₉OH

• Molecular Weight: 97.20 g/mol

• CAS Number: 148587-12-6

• Isotopic Enrichment: ≥ 98 atom % D

• Chemical Class: Deuterated primary alcohol

• Solubility: Slightly soluble in water; readily soluble in ethanol, ether, and common organic solvents

APPLICATIONS  of  n-Pentyl-2,2,3,3,4,4,5,5,5-d9 Alcohol | CAS 148587-12-6

• Mass Spectrometry Internal Standard:
  Frequently employed as an internal standard for GC-MS and LC-MS analysis of n-pentanol, short-chain alcohols, and volatile organic compounds (VOCs). Its stable isotope labeling ensures precise mass separation for accurate quantitation.

• Isotope Dilution Quantification:
  Facilitates robust quantitative analysis of alcohol-containing matrices such as food products, fragrance formulations, biofuels, and environmental samples.

• Metabolic and Biochemical Studies:
  Used in metabolic tracing experiments to investigate alcohol oxidation pathways, enzymatic activity, and lipid or VOC biosynthesis.

• Quality Control and Method Validation:
  Supports method development, calibration curve construction, extraction efficiency evaluation, and recovery studies in analytical laboratories.

• NMR Studies:
  The deuterated carbon backbone allows its application in ²H NMR experiments and helps achieve background signal suppression in complex matrices.

ADVANTAGES  of  n-Pentyl-2,2,3,3,4,4,5,5,5-d9 Alcohol | CAS 148587-12-6

• High deuterium incorporation provides unambiguous mass distinction from native n-pentanol.

• Maintains identical chromatographic and chemical behavior with the unlabeled compound for precise co-elution comparison.

• Suitable for high-sensitivity and high-accuracy quantitative workflows.

• Stable across a wide range of storage and analytical conditions, ensuring long-term usability.

HANDLING AND SAFETY

• General Handling: Avoid contact with eyes and skin; use in a well-ventilated environment.

• PPE: Wear gloves, eye protection, and a lab coat during handling.

• Stability: Stable under standard laboratory conditions; avoid oxidizing agents and high heat.

• Disposal: Dispose of according to institutional and regional regulations for organic solvents and analytical reagents.

SUMMARY
n-Pentyl-2,2,3,3,4,4,5,5,5-d₉ alcohol (CAS 148587-12-6) is a high-purity, stable isotope-labeled primary alcohol widely used in analytical chemistry, isotopic quantification, metabolic studies, and method development. Its excellent chemical stability, high isotopic enrichment, and close structural match to native n-pentanol make it an indispensable tool for accurate mass spectrometric analysis and advanced research workflows.