p-Octopamine-α,β,β-d3 HCl | CAS 1219803-62-9

OVERVIEW  of  p-Octopamine-α,β,β-d3 HCl | CAS 1219803-62-9

 

p-Octopamine-α,β,β-d₃ HCl (CAS 1219803-62-9) is a deuterium-labeled catecholamine analogue featuring three deuterium atoms substituted at the α and β positions of the side chain. As a stable isotope-labeled version of p-octopamine, this compound provides excellent mass differentiation while maintaining identical biochemical properties to the non-labeled molecule.
It is widely used in LC-MS/MS quantitative analysis of neurotransmitters, metabolic pathway studies, biomarker research, and pharmacokinetic evaluation. The hydrochloride salt form enhances stability, solubility, and compatibility with aqueous biological sample matrices. ResolveMass Laboratories Inc. supplies this compound with high isotopic enrichment, purity, and batch-to-batch consistency suitable for rigorous analytical and clinical research workflows.

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CHEMICAL INFORMATION

Chemical Name: p-Octopamine-α,β,β-d₃ hydrochloride
Synonyms: Deuterated p-octopamine HCl, Octopamine-d₃ HCl
CAS Number: 1219803-62-9
Molecular Formula: C₈H₈D₃NO₂ · HCl
Molecular Weight:  229.64 g/mol
Isotopic Enrichment: ≥98 atom % D
Functional Groups: Phenolic hydroxyls, primary amine (protonated), deuterated alkyl chain

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APPLICATIONS  of  p-Octopamine-α,β,β-d3 HCl | CAS 1219803-62-9

• Neurotransmitter Quantitation (LC-MS/MS): A highly reliable internal standard for measuring octopamine in plasma, urine, tissue, and cell cultures.

• Biomarker Studies: Supports metabolic and neurological research involving catecholaminergic pathways.

• Pharmacokinetics & Drug Metabolism: Used in ADME profiling and metabolic stability studies.

• Clinical & Diagnostic Research: Ideal for assays related to sympathetic nervous system activity and stress-response biomarkers.

• Isotope-Dilution Mass Spectrometry (IDMS): Ensures highly accurate quantitation in complex biological matrices.

• Biochemical & Metabolic Pathway Analysis: Enables tracing of metabolic conversions involving catecholamines.

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FEATURES & BENEFITS

• High Isotopic Purity: Ensures excellent mass separation for clean MS detection.

• Hydrochloride Salt Form: Provides improved stability and high aqueous solubility.

• Biochemical Equivalence: Mimics native octopamine for precise isotope-dilution analysis.

• Low Background Noise: Minimizes matrix interference in LC-MS/MS assays.

• Versatile Research Use: Suitable for neurochemistry, pharmacology, clinical diagnostics, and biomarker discovery.

• Consistent Quality: Manufactured to high standards to support regulated laboratory applications.

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SUMMARY

p-Octopamine-α,β,β-d₃ HCl (CAS 1219803-62-9) is a premium deuterium-labeled catecholamine standard optimized for neurotransmitter quantitation and metabolic research. Its high stability, solubility, and isotopic enrichment make it ideal for LC-MS/MS workflows used in neurochemical, pharmacokinetic, and biomarker studies. Produced by ResolveMass Laboratories Inc., this compound ensures exceptional reproducibility and accuracy across analytical applications.

 

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