Styrene -d3 | CAS 3814-93-5

OVERVIEW
Styrene -d3 | CAS 3814-93-5 also known as deuterated styrene, is a stable isotopically labeled analog of styrene (C8H8), in which three hydrogen atoms are replaced by deuterium atoms. Its CAS number is 3814-93-5. This compound is primarily used as an internal standard in mass spectrometry (MS), gas chromatography-mass spectrometry (GC-MS), and other analytical techniques that require precise quantification of styrene in complex matrices. The incorporation of deuterium provides a distinct mass shift compared to non-labeled styrene, enabling accurate detection and quantification without interference from naturally occurring styrene.

Styrene-d3 is highly valued in research, environmental monitoring, and industrial applications due to its chemical stability, high isotopic purity, and reproducible performance in analytical workflows. It is particularly useful in studies where precise measurement of styrene levels is critical, including polymer synthesis monitoring, occupational exposure assessment, and environmental pollutant analysis.

CHEMICAL INFORMATION

• Chemical Name: Styrene-d3

• CAS Number: 3814-93-5

• Molecular Formula: C8H5D3

• Molecular Weight: 107.17 g/mol

• Purity: Typically ≥98% (isotopic purity)

ISOTOPIC LABELING AND APPLICATIONS  
Styrene-d3 serves as a deuterated standard that is invaluable in isotope dilution mass spectrometry (IDMS). Its primary function is to act as an internal standard for the quantitative analysis of styrene in various samples. The three deuterium atoms provide a mass difference from native styrene, allowing accurate separation in MS detection while maintaining nearly identical chemical and physical properties.

Key Applications Include:

1. Analytical Chemistry: As an internal standard for GC-MS and LC-MS analyses, Styrene-d3 ensures high accuracy and precision in quantifying styrene levels in complex mixtures.

2. Environmental Monitoring: Used to assess styrene contamination in air, water, soil, and industrial effluents, supporting regulatory compliance.

3. Polymer and Material Research: Essential in monitoring polymerization reactions involving styrene monomers, providing reliable data for reaction kinetics and process optimization.

4. Occupational Health Studies: Helps in evaluating styrene exposure in workers, particularly in the plastics and synthetic rubber industries.

5. Forensic and Toxicological Studies: Assists in the identification and quantification of styrene metabolites in biological samples.

ADVANTAGES OF USING Styrene -d3 | CAS 3814-93-5

• High Accuracy in Quantification: The deuterium labeling allows precise differentiation from natural styrene, reducing measurement errors.

• Chemical Stability: Stable under ambient conditions, reducing decomposition or isotopic exchange during storage and analysis.

• Versatile Compatibility: Soluble in a range of organic solvents, compatible with multiple analytical platforms.

• Reproducibility: Offers consistent performance across batches, making it suitable for routine laboratory applications.

• Regulatory Compliance Support: Facilitates accurate styrene quantification for meeting environmental and occupational safety regulations.

HANDLING AND STORAGE
Styrene-d3 should be handled under standard laboratory safety conditions. Use appropriate personal protective equipment (PPE) including gloves and eye protection. Avoid inhalation or direct skin contact, as styrene derivatives may be irritants. Store in a cool, dry place, away from light and sources of ignition. Proper storage ensures long-term isotopic integrity and chemical stability.

QUALITY AND CERTIFICATION
ResolveMass Laboratories Inc. provides Styrene-d3 with guaranteed high isotopic purity, validated through rigorous quality control protocols. Each batch is accompanied by a certificate of analysis (CoA), detailing isotopic enrichment, chemical purity, and physical properties. This ensures traceability, reliability, and reproducibility for analytical and research applications.

SUMMARY
Styrene-d3 (CAS 3814-93-5) is an essential deuterated standard for precise styrene quantification in analytical chemistry, environmental monitoring, polymer research, and occupational health studies. Its high isotopic purity, chemical stability, and compatibility with various solvents and analytical instruments make it a trusted choice for laboratories worldwide. By using Styrene-d3, researchers and analysts can achieve accurate, reproducible, and regulatory-compliant results, ensuring confidence in every measurement.

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