1-Hexadecanol-d31 | CAS 203633-15-2

OVERVIEW  of  1-Hexadecanol-d31 | CAS 203633-15-2
1-Hexadecanol-d₃₁ (CAS 203633-15-2) is a fully deuterated analog of 1-hexadecanol (cetyl alcohol), in which all 31 exchangeable hydrogen atoms are replaced with deuterium. This long-chain fatty alcohol serves as a stable isotope-labeled compound for use in lipidomics, metabolic studies, and mass spectrometric quantification of long-chain alcohols and related lipids. Due to its chemical stability and identical physicochemical behavior to the non-deuterated analog, it is ideal for use as an internal standard in various analytical applications.

CHEMICAL INFORMATION

• Name: 1-Hexadecanol-d₃₁

• Molecular Formula: C₁₆D₃₃OD

• Molecular Weight: 273.64 g/mol

• CAS Number: 203633-15-2

• Isotopic Enrichment: ≥ 98 atom % D

• Chemical Class: Deuterated long-chain fatty alcohol

• Solubility: Insoluble in water; soluble in organic solvents such as ethanol, chloroform, and ether

APPLICATIONS  of  1-Hexadecanol-d31 | CAS 203633-15-2

• Mass Spectrometry Internal Standard:
  Used as an internal standard in GC-MS and LC-MS analyses for quantifying long-chain alcohols, wax esters, and lipids in biological or environmental samples.

• Lipidomics and Metabolomics:
  Enables accurate isotope dilution analysis for profiling and quantifying fatty alcohols and related lipid species in plasma, serum, and tissue extracts.

• Stable Isotope Tracer Studies:
  Utilized to trace lipid metabolism, biosynthesis, and bioconversion pathways in metabolic flux analysis.

• Calibration and Quantification:
  Ideal for constructing standard curves in quantitative GC-MS assays where isotopic fidelity is crucial.

• Pharmaceutical and Cosmetic Research:
  Applied as a reference compound in studies involving fatty alcohol derivatives, surfactants, and personal care formulations.

ADVANTAGES  of  1-Hexadecanol-d31 | CAS 203633-15-2

• Fully deuterated (d₃₁) for clear mass differentiation from native 1-hexadecanol.

• Chemically and physically identical to the non-labeled form—ensures consistent behavior during extraction and chromatography.

• High isotopic purity ensures reliable and reproducible quantitation.

• Stable and easy to handle under standard laboratory conditions.

HANDLING AND SAFETY

• Handling Precautions: Avoid contact with skin and eyes; handle under dry, inert conditions if possible.

• Protective Equipment: Use gloves, lab coat, and safety goggles.

• Storage: Keep tightly sealed in a cool, dry, and well-ventilated area.

• Stability: Stable at ambient temperature under normal storage conditions.

• Disposal: Dispose of according to institutional and local environmental regulations for organic chemicals.

SUMMARY
1-Hexadecanol-d₃₁ (CAS 203633-15-2) is a high-purity, fully deuterated fatty alcohol tailored for quantitative analytical applications in lipid and metabolic research. Its high isotopic enrichment and stability make it an indispensable standard for accurate mass spectrometric quantification, metabolic pathway tracing, and lipidomics method validation.