2-chloro-3,5-dinitropyridine | CAS 2578-45-2

PRODUCT NAME
2-Chloro-3,5-Dinitropyridine

CAS NUMBER
2578-45-2

SYNONYMS
2-Chloro-3,5-DNP, 2-Chloro-3,5-dinitro-1-pyridine

OVERVIEW
2-chloro-3,5-dinitropyridine | CAS 2578-45-2  is a highly specialized chemical intermediate widely used in organic synthesis, agrochemical research, and pharmaceutical development. Its distinct chemical structure, featuring a pyridine ring substituted with chloro and nitro groups, renders it a versatile building block in the synthesis of various heterocyclic compounds. This compound is particularly valued for its reactivity and selectivity in nucleophilic substitution and cross-coupling reactions.

ResolveMass Laboratories Inc. supplies high-purity 2-Chloro-3,5-Dinitropyridine, ensuring consistent quality and performance for laboratory applications. Our rigorous quality control procedures guarantee a reliable product suitable for research, development, and pilot-scale synthesis.

CHEMICAL INFORMATION

• Molecular Formula: C5H2ClN3O4

• Molecular Weight: 203.54 g/mol

• Purity: ≥98% (HPLC)

STRUCTURE & REACTIVITY
The chemical structure of 2-Chloro-3,5-Dinitropyridine features a pyridine core with electron-withdrawing nitro groups at positions 3 and 5, and a reactive chloro substituent at position 2. This combination of electron-withdrawing groups and halogen functionality enhances the compound’s electrophilicity, making it highly reactive in substitution reactions.

Key chemical characteristics include:

• Electrophilic substitution capability: The presence of nitro groups activates the pyridine ring toward nucleophilic attack.

• Halogen reactivity: The chlorine atom at the 2-position can undergo nucleophilic substitution to form derivatives or heterocycles.

• Stability: Under standard storage conditions, the compound is stable, though it should be protected from strong acids, bases, and light to prevent degradation.

APPLICATIONS
2-chloro-3,5-dinitropyridine | CAS 2578-45-2  finds extensive use in the following areas:

1. Pharmaceutical Research:

   • Used as a building block in the synthesis of heterocyclic compounds, including pyridine-based drugs.

   • Serves as a key intermediate in the development of kinase inhibitors, antimicrobial agents, and other bioactive molecules.

2. Agrochemical Development:

   • Applied in the preparation of herbicides, fungicides, and insecticides.

   • Acts as a precursor for nitro-substituted pyridine derivatives with improved biological activity.

3. Organic Synthesis:

   • Useful in nucleophilic aromatic substitution (SNAr) reactions.

   • Serves as a versatile intermediate in multi-step synthetic routes for complex molecules.

4. Chemical Research:

   • Employed in mechanistic studies of pyridine reactivity.

   • Enables exploration of novel heterocyclic frameworks with potential pharmaceutical or material applications.

QUALITY ASSURANCE
ResolveMass Laboratories Inc. ensures that each batch of 2-Chloro-3,5-Dinitropyridine undergoes stringent analytical testing, including:

• High-Performance Liquid Chromatography (HPLC) for purity verification

• Nuclear Magnetic Resonance (NMR) spectroscopy for structural confirmation

• Elemental analysis to confirm composition

These quality measures ensure that researchers receive a product that meets rigorous laboratory standards and delivers reliable results.

CONCLUSION
2-Chloro-3,5-Dinitropyridine is an essential intermediate for pharmaceutical, agrochemical, and chemical research applications. Its unique reactivity, coupled with high purity from ResolveMass Laboratories, ensures dependable performance for synthetic chemists and researchers pursuing advanced organic synthesis projects. By choosing our product, laboratories can confidently execute complex transformations and achieve reproducible results.