(3aR,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyldihydrofuro[3,4-d][1,3]dioxol-4(3aH)-one | CAS 30725-00-9

OVERVIEW
(3aR,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyldihydrofuro[3,4-d][1,3]dioxol-4(3aH)-one | CAS 30725-00-9  is a highly versatile organic intermediate widely utilized in pharmaceutical research, synthetic chemistry, and oligosaccharide synthesis. Its unique bicyclic structure, featuring a furanose-dioxolane framework, makes it an important building block for complex molecules, including nucleoside analogs, carbohydrate derivatives, and other biologically active compounds.

This compound is specifically valued for its stereochemical purity, offering well-defined chiral centers at positions 3a, 6, and 6a. Such stereochemical precision is critical in drug synthesis, as it allows chemists to create target molecules with high activity and selectivity while minimizing side reactions and by-products.

CHEMICAL INFORMATION

• IUPAC Name: (3aR,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyldihydrofuro[3,4-d][1,3]dioxol-4(3aH)-one

• CAS Number: 30725-00-9

• Molecular Formula: C8H12O5

• Molecular Weight: 188.18 g/mol

• Chemical Structure: Bicyclic furan-dioxolane with a hydroxymethyl substituent at the 6-position

KEY FEATURES & BENEFITS

1. Chiral Purity: The compound’s defined stereochemistry ensures high enantiomeric purity, which is essential for producing biologically active molecules with predictable pharmacological properties.

2. Synthetic Versatility: Its functional groups, including a reactive hydroxymethyl moiety and ketone functionality, allow for diverse chemical transformations such as oxidation, reduction, protection/deprotection, and coupling reactions.

3. Pharmaceutical Applications: Frequently used as an intermediate in the synthesis of nucleoside analogs, antiviral compounds, and carbohydrate-based drug candidates.

4. Research Reliability: Produced under stringent quality standards to ensure consistency, making it ideal for medicinal chemistry, structure-activity relationship (SAR) studies, and high-throughput screening.

APPLICATIONS  of  (3aR,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyldihydrofuro[3,4-d][1,3]dioxol-4(3aH)-one | CAS 30725-00-9

• Pharmaceutical Synthesis: Acts as a precursor in the development of antiviral and anticancer nucleoside analogs. Its bicyclic structure provides a rigid scaffold that enhances molecular stability and interaction with target enzymes.

• Oligosaccharide & Carbohydrate Chemistry: Used in the synthesis of complex sugars, glycoconjugates, and glycomimetics. Its stereochemical fidelity ensures correct glycosidic linkage formation in oligosaccharide synthesis.

• Organic Synthesis & Medicinal Chemistry: Serves as a versatile building block in multi-step synthetic pathways, enabling the construction of diverse small molecules with pharmaceutical relevance.

• Chiral Building Block: The compound’s defined stereochemistry makes it an ideal starting material for asymmetric synthesis, enabling the creation of enantiomerically pure molecules for research and drug discovery.

QUALITY & COMPLIANCE
ResolveMass Laboratories Inc. maintains rigorous quality control for all chemical intermediates, including CAS 30725-00-9. Each batch undergoes detailed analytical verification to ensure chemical purity, stereochemical integrity, and absence of detectable impurities. Our commitment to compliance ensures that the compound meets the standards required for advanced research and pharmaceutical applications.

SUMMARY
(3aR,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyldihydrofuro[3,4-d][1,3]dioxol-4(3aH)-one (CAS 30725-00-9) is a premium chiral intermediate for pharmaceutical and synthetic chemistry applications. Its stereochemical precision, chemical versatility, and high purity make it an indispensable tool for chemists developing complex molecules, nucleoside analogs, and carbohydrate derivatives. ResolveMass Laboratories Inc. ensures reliable supply, consistent quality, and comprehensive support for researchers leveraging this compound in cutting-edge scientific studies.