5-chloro-2-(4-methoxybenzyl)-4-(trifluoromethyl)pyridazin-3(2H)-one | CAS 2381044-50-2

OVERVIEW
5-chloro-2-(4-methoxybenzyl)-4-(trifluoromethyl)pyridazin-3(2H)-one | CAS 2381044-50-2, is a highly specialized heterocyclic compound widely utilized in pharmaceutical research and chemical synthesis. This molecule features a pyridazinone core with unique substituents, including a chloro group, a trifluoromethyl moiety, and a methoxybenzyl group, which collectively contribute to its distinct chemical properties and versatility in medicinal chemistry applications.

At ResolveMass Laboratories Inc., we provide this compound with high purity and stringent quality control standards, making it suitable for research purposes, structure-activity relationship (SAR) studies, and advanced drug discovery programs.

CHEMICAL INFORMATION

• Chemical Name: 5-Chloro-2-(4-methoxybenzyl)-4-(trifluoromethyl)pyridazin-3(2H)-one

• CAS Number: 2381044-50-2

• Molecular Formula: C13H9ClF3N2O2

• Molecular Weight: 318.68 g/mol

• Chemical Structure: Pyridazinone core substituted with chloro (Cl) at position 5, trifluoromethyl (CF3) at position 4, and 4-methoxybenzyl at position 2

This compound is classified under advanced heterocyclic intermediates, and its trifluoromethyl and methoxybenzyl substituents often contribute to improved lipophilicity and metabolic stability, properties highly valuable in drug design and development.

PHYSICAL AND CHEMICAL PROPERTIES
5-Chloro-2-(4-methoxybenzyl)-4-(trifluoromethyl)pyridazin-3(2H)-one exhibits a solid-state appearance, with moderate solubility in common organic solvents such as dimethyl sulfoxide (DMSO), dimethylformamide (DMF), and ethanol. Its trifluoromethyl group imparts chemical robustness and contributes to electron-withdrawing effects, which can influence reactivity in subsequent synthetic transformations. The chloro and methoxybenzyl functionalities further enable derivatization and fine-tuning of pharmacokinetic properties for medicinal chemistry applications.

APPLICATIONS IN RESEARCH AND DEVELOPMENT of 5-chloro-2-(4-methoxybenzyl)-4-(trifluoromethyl)pyridazin-3(2H)-one | CAS 2381044-50-2

This compound is primarily utilized in pharmaceutical and agrochemical research. Its pyridazinone core serves as a versatile scaffold for the development of bioactive molecules. Key applications include:

1. Medicinal Chemistry: As a heterocyclic intermediate, it is employed in the synthesis of novel therapeutic candidates targeting various biological pathways. The trifluoromethyl group often enhances metabolic stability and membrane permeability, crucial for drug design.

2. SAR (Structure-Activity Relationship) Studies: Researchers leverage this molecule to explore the effects of substituent modifications on biological activity. Its unique combination of chloro, methoxybenzyl, and trifluoromethyl groups allows systematic investigation of chemical and pharmacological properties.

3. Chemical Synthesis: This compound serves as a building block for more complex heterocyclic molecules. Its functional groups are reactive under controlled conditions, enabling derivatization for specialized synthetic routes.

4. Pharmacokinetic Optimization: The trifluoromethyl and methoxybenzyl substituents contribute to desirable physicochemical properties, such as enhanced solubility in organic solvents and improved lipophilicity, which are critical parameters in drug development.

QUALITY AND COMPLIANCE
At ResolveMass Laboratories Inc., we maintain strict quality control protocols to ensure that all compounds meet the highest standards of purity and reproducibility. 5-Chloro-2-(4-methoxybenzyl)-4-(trifluoromethyl)pyridazin-3(2H)-one is supplied with detailed characterization data, including NMR, LC-MS, and HPLC profiles, providing researchers with reliable and fully traceable analytical information.

WHY CHOOSE RESOLVEMASS LABORATORIES INC.

• High Purity and Consistency: We provide compounds with verified purity suitable for sensitive research applications.

• Comprehensive Documentation: Each batch comes with analytical certificates and full characterization data.

• Global Shipping and Support: Efficient logistics ensure timely delivery to labs worldwide, accompanied by expert technical support.

• Research-Grade Supply: Ideal for early-stage drug discovery, SAR studies, and advanced heterocyclic synthesis projects.

  CONCLUSION
  5-Chloro-2-(4-methoxybenzyl)-4-(trifluoromethyl)pyridazin-3(2H)-one (CAS 2381044-50-2) is a versatile and highly valuable heterocyclic compound in pharmaceutical and chemical research. With its well-defined chemical structure, functional versatility, and consistent high quality, it is a critical tool for scientists engaged in medicinal chemistry, drug discovery, and synthetic organic chemistry.

  PubChem CID
  1479655