5-Hydroxy-2-methyl-d3-pyridine-3,4,6-d3 | CAS 2645412-74-2

OVERVIEW of 5-Hydroxy-2-methyl-d3-pyridine-3,4,6-d3 | CAS 2645412-74-2
5-Hydroxy-2-methyl-d3-pyridine-3,4,6-d3 is a fully deuterium-labelled pyridine derivative containing six deuterium atoms strategically incorporated into both the methyl substituent and the aromatic ring. This isotopically enriched compound is widely used as an internal standard, tracer molecule, and reference material in analytical chemistry, metabolic studies, pharma research, and advanced isotopic investigations. Its enhanced stability and mass shift make it highly suitable for LC-MS/MS applications requiring high precision and low detection limits.

CHEMICAL INFORMATION

• Chemical Name: 5-Hydroxy-2-methyl-d3-pyridine-3,4,6-d3

• CAS Number: 2645412-74-2

• Isotopic Labelling: d6 (3 deuteriums on the methyl group + 3 deuteriums on the pyridine ring)

• Class: Deuterated pyridine derivative

• Key Characteristics:

  • Strong mass spectral separation

  • Excellent stability for long-term analytical use

  • High compatibility with chromatographic systems

APPLICATIONS of 5-Hydroxy-2-methyl-d3-pyridine-3,4,6-d3 | CAS 2645412-74-2

• Internal Standard for LC-MS/MS: Ideal for quantification of pyridine-based metabolites, drug impurities, or degradation products.

• Pharmaceutical Research: Supports studies on drug metabolism, mechanism elucidation, and labelled analog comparisons.

• Stable Isotope Tracing: Enables pathway tracking and kinetic isotope studies involving pyridine-containing molecules.

• Analytical Method Development: Used for calibration, validation, and system suitability testing in regulated analytical workflows.

• Chemical & Biochemical Research: Serves as a labelled reference compound for reaction mechanism studies involving pyridine chemistry.

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