Acetic acid-d4 | CAS 1186-52-3

OVERVIEW
Acetic acid-d4 | CAS 1186-52-3 is a stable, deuterium-labeled analog of acetic acid, widely used in advanced analytical and synthetic applications. In this compound, the three hydrogen atoms of the methyl group in conventional acetic acid are replaced with deuterium, resulting in a molecule with the formula CD₃COOD. This isotopically enriched reagent is essential for researchers and scientists requiring high-precision studies in mass spectrometry, nuclear magnetic resonance (NMR) spectroscopy, and other isotopic labeling applications.

At ResolveMass Laboratories Inc., we provide high-purity acetic acid-d4, ensuring reliability and reproducibility in sensitive analytical workflows. Each batch undergoes stringent quality control to meet the demanding standards of research and pharmaceutical development.

CHEMICAL INFORMATION

• Chemical Name: Acetic acid-d4

• CAS Number: 1186-52-3

• Molecular Formula: CD₃COOD

• Molecular Weight: 64.08 g/mol

• Physical Appearance: Colorless liquid

• Purity: ≥99% (typical, depending on grade)

• Isotopic Enrichment: High deuterium content (≥98%)

• Hazard Classification: Corrosive; flammable liquid

Acetic acid-d4 is chemically analogous to standard acetic acid but offers unique properties due to deuterium substitution. The isotopic labeling slightly alters the physical and spectroscopic characteristics, making it indispensable for precise experimental applications.

APPLICATIONS  of  Acetic acid-d4 | CAS 1186-52-3

1. Nuclear Magnetic Resonance (NMR) Spectroscopy
   Acetic acid-d4 is commonly used as a deuterated solvent or reference in NMR spectroscopy. Its high deuterium content reduces proton background signals, improving spectral resolution and accuracy. Researchers utilize it for proton (^1H) and carbon (^13C) NMR experiments, as well as for studying reaction kinetics and molecular dynamics.

2. Mass Spectrometry (MS) and Isotopic Labeling
   In mass spectrometry, acetic acid-d4 serves as a labeled internal standard or reagent. Its unique mass shift compared to non-labeled acetic acid allows for precise quantification and calibration of analytes, particularly in metabolomics, proteomics, and pharmaceutical analysis.

3. Organic Synthesis
   Acetic acid-d4 can be employed in the synthesis of deuterated compounds, which are valuable in drug development, mechanistic studies, and tracer experiments. Incorporating deuterium into molecular scaffolds provides insights into reaction pathways and metabolic stability.

4. Pharmaceutical and Biochemical Research
   Deuterated acetic acid is frequently used in pharmaceutical research to study isotopic effects on drug metabolism, enzyme activity, and pharmacokinetics. Its role in tracer studies and labeled compound synthesis makes it a critical tool for life science laboratories.

ADVANTAGES OF USING ACETIC ACID-d4 FROM RESOLVEMASS LABORATORIES

• High Purity and Isotopic Integrity: Each batch is rigorously tested to ensure ≥99% purity and high deuterium enrichment, providing consistent performance for sensitive experiments.

• Reliable Supply: Our robust production and quality control processes ensure that researchers receive a dependable and reproducible product.

• Comprehensive Technical Support: ResolveMass Laboratories Inc. offers expert guidance on product handling, storage, and application to maximize experimental success.

• Compliance and Safety: All products are manufactured and handled under strict laboratory safety standards, ensuring traceability and regulatory compliance.

CONCLUSION
Acetic acid-d4 | CAS 1186-52-3  is a critical reagent for advanced analytical, synthetic, and pharmaceutical applications. Its high purity, isotopic enrichment, and reliability make it an essential tool for researchers conducting NMR spectroscopy, mass spectrometry, organic synthesis, and biochemical studies. ResolveMass Laboratories Inc. is committed to delivering high-quality deuterated compounds backed by stringent quality control and technical expertise, enabling scientists to achieve reproducible and accurate results in every experiment.

By choosing ResolveMass Laboratories for your acetic acid-d4 supply, laboratories gain access to a product that meets the highest standards of scientific research and supports cutting-edge innovation.