Cyclohexene-d10 | CAS No.: 1603-55-0

Cyclohexene-d10 | CAS No.: 1603-55-0

Molecular Formula: C₆D₁₀
Molecular Weight: 92.21 g/mol
Synonyms: Fully deuterated cyclohexene, 1,2,3,4,5,6,6,6,5,5-Decadeutero-cyclohexene, Cyclohexene-D10, Perdeutero-cyclohexene, Cyclohexene-d₁₀ isotopic standard, Cyclohexene-d₁₀ NMR solvent reference.

Product Overview

Cyclohexene-d10 is a fully deuterated analog of cyclohexene, where all ten hydrogen atoms are replaced by deuterium (²H or D). This isotopically labeled compound is widely used in nuclear magnetic resonance (NMR) spectroscopy, mass spectrometry (MS), and mechanistic organic chemistry to study reaction pathways, hydrogen exchange kinetics, and isotope effects.

As a high-purity deuterium-labeled hydrocarbon, Cyclohexene-d10 is particularly valuable as a non-polar NMR solvent, a reaction intermediate in isotopic labeling, and a stable isotope internal standard for gas-phase and solution-phase studies. Its full deuteration ensures reduced background interference and high signal resolution in analytical experiments.

ResolveMass Laboratories Inc. supplies Cyclohexene-d10 with exceptional isotopic enrichment (≥98 atom % D) and chemical purity, ideal for advanced analytical, industrial, and academic research applications.

Applications and Scientific Importance of Cyclohexene-d10 | CAS No.: 1603-55-0

1. NMR Spectroscopy and Solvent Use

Cyclohexene-d10 is commonly employed as a non-protonated solvent or a reference standard in NMR studies, especially for samples sensitive to protic interference. The absence of hydrogen signals simplifies proton spectra and enhances the visibility of solute resonances. It is also used as an internal standard for quantitative NMR (qNMR) analysis of organic compounds.

2. Mechanistic and Kinetic Studies

Deuterated cyclohexene is a key compound for investigating hydrogen–deuterium exchange reactions, dehydrogenation mechanisms, and isotopic kinetic isotope effects (KIE). The strong C–D bond provides insight into energy barriers, reaction intermediates, and transition-state behavior in catalytic hydrogenation and oxidation reactions.

3. Mass Spectrometry (MS) Internal Standard

In GC-MS or LC-MS workflows, Cyclohexene-d10 serves as a mass reference or internal calibration compound for hydrocarbon quantification. The presence of deuterium shifts its molecular ion peaks (M+10), allowing easy distinction from native cyclohexene in complex mixtures.

4. Isotope Labeling and Synthesis

Cyclohexene-d10 can also act as a precursor for synthesizing labeled intermediates and deuterated polymers. Its high deuterium content makes it suitable for controlled deuterium incorporation in organic synthesis, where the stable isotope acts as a tracer or mechanistic probe.

5. Environmental and Combustion Studies

Deuterated hydrocarbons like Cyclohexene-d10 are used in combustion kinetics and atmospheric chemistry research to model isotope effects in oxidation processes, radical reactions, and energy transfer dynamics. Researchers can evaluate reaction rate differences between hydrogenated and deuterated analogs to better understand radical propagation pathways.

Analytical Advantages of Cyclohexene-d10 | CAS No.: 1603-55-0

• Enhanced Signal Clarity: Absence of proton peaks minimizes background interference in NMR analysis.

• Stable and Non-reactive: The fully saturated deuterated structure exhibits excellent stability under standard storage and analytical conditions.

• Quantitative Reliability: High isotopic and chemical purity ensures reproducible results in isotope-dilution mass spectrometry (IDMS).

• Versatile Compatibility: Compatible with various spectroscopic, chromatographic, and kinetic systems.

Storage and Handling

Cyclohexene-d10 should be handled under anhydrous and inert conditions (e.g., nitrogen or argon atmosphere) to prevent oxidation or polymerization. The compound is volatile and should be stored in tightly sealed amber vials at low temperature, away from heat and direct sunlight. Always follow appropriate laboratory safety protocols when handling deuterated hydrocarbons.

Ordering Information

• Pack Sizes: 1 mL, 5 mL, 10 mL (custom sizes available upon request)

• Purity: ≥99% (chemical), ≥98 atom % D (isotopic)

• Lead Time: 2–4 weeks

• Catalog No.: RMCHX-D10

For bulk inquiries, custom labeling, or higher isotopic enrichment levels, contact ResolveMass Laboratories Inc. Our team specializes in custom synthesis of deuterium- and ¹³C-labeled compounds for analytical and pharmaceutical R&D applications.

Conclusion

Cyclohexene-d10 (CAS No.: 1603-55-0) is a high-value isotopically labeled reagent used across multiple disciplines—from NMR and MS analysis to mechanistic chemistry and isotope tracing. Its high isotopic enrichment, superior stability, and analytical reliability make it indispensable for researchers seeking precise, reproducible results.

At ResolveMass Laboratories Inc., we deliver deuterium-labeled compounds with uncompromising quality and consistency — supporting your analytical accuracy, synthetic innovation, and research excellence.