Deuterated α-Methylstyrene-d10 | CAS 10362-82-0

PRODUCT OVERVIEW

Deuterated α-Methylstyrene-d10 | CAS 10362-82-0  is a fully deuterated analog of α-methylstyrene in which all exchangeable hydrogen atoms on the aromatic ring and the α-methyl group have been replaced with deuterium (D, heavy hydrogen). This isotopically labeled intermediate is a high-purity specialty chemical designed for advanced research applications such as internal standards in mass spectrometry (MS), mechanistic studies, metabolic profiling, and tracer experiments.

Deuterium labeling enhances molecular stability under analytical conditions and shifts mass spectral characteristics without altering core chemical functionality. ResolveMass Laboratories Inc. supplies this compound with rigorous quality control, ensuring high isotopic purity, minimal protium content, and consistent batch-to-batch reproducibility.

The structural formula may be represented as C₉D₁₀, where deuterium atoms replace all hydrogen atoms in the aromatic and aliphatic framework of α-methylstyrene.

KEY FEATURES & BENEFITS

• High Isotopic Purity: >98% deuterium incorporation minimizes background interference in analytical assays.

• Mass Spectrometry Compatibility: Ideal as an internal standard for quantitative LC-MS/MS or GC-MS analyses due to predictable mass shift.

• Analytical Precision: Enhanced signal distinction improves quantification accuracy in complex matrices.

• Research Utility: Suitable for isotope-tracing studies in physical organic chemistry and reaction mechanism investigations.

• Chemical Consistency: Manufactured under strict quality protocols to meet research and pharmaceutical standards.

CHEMICAL IDENTIFICATION

• Name: Deuterated α-Methylstyrene-d₁₀

• CAS Number: 10362-82-0

• Molecular Formula: C₉D₁₀

• Molecular Weight: 128.24 g/mol

• Deuteration: >98% (target specification)

• Purity: Typically ≥98% (GC/¹H NMR or equivalent analytical confirmation)

APPLICATIONS  of  Deuterated α-Methylstyrene-d10 | CAS 10362-82-0

Mass Spectrometry Internal Standard

Deuterated analogs remain among the best internal standards for quantitative MS workflows because isotopic labeling shifts mass without altering chromatographic behavior. Deuterated α-Methylstyrene-d₁₀ provides a well-resolved mass difference from the native compound, enabling accurate calibration and compensation for matrix effects.

Mechanistic and Kinetic Studies

In physical organic chemistry, deuterium substitution can affect reaction rates through the kinetic isotope effect (KIE). Researchers use deuterated substrates like α-Methylstyrene-d₁₀ to probe rate-limiting steps, elucidate transition states, and refine theoretical models.

Metabolic Pathway Tracing

Deuterium-labeled compounds facilitate metabolic and biotransformation studies by enabling straightforward tracing of labeled atoms through pathways using high resolution MS. This supports metabolomics, pharmacokinetics, and biochemical pathway mapping.

NMR Spectroscopy

Although deuteration reduces ¹H NMR signal intensity for labeled sites, deuterated compounds serve as solvents or references in specialized NMR experiments or for background suppression in complex mixture analysis.

Isotope Dilution Assays

Working as a reference material in isotope dilution analysis, Deuterated α-Methylstyrene-d₁₀ supports high-accuracy quantitative determinations, particularly where structural analogs are measured in trace amounts.

PHYSICAL & CHEMICAL PROPERTIES

Note: Exact data may vary by batch; certificates of analysis (COAs) are provided upon request.

QUALITY CONTROL & ANALYTICAL DATA

Each lot of Deuterated α-Methylstyrene-d₁₀ undergoes comprehensive analysis including:

• ¹H and ²H NMR Spectroscopy: Confirms deuteration level and structural integrity.

• GC/MS or LC/MS Profiling: Verifies isotopic distribution and purity.

• Chromatographic Purity Assessment: GC or HPLC confirms absence of major impurities.

• Moisture and Volatile Analysis: Ensures minimal residual solvents or water content.

ResolveMass Laboratories Inc. adheres to documented quality systems, and detailed lot COAs are available on request or accessible through our customer portal.

WHY RESOLVEMASS LABORATORIES?

ResolveMass Laboratories Inc. is committed to delivering high-quality isotopically labeled standards and specialty chemicals with rigorous analytical validation and reliable supply. Our focus is on precision, consistency, and customer support, equipping laboratories worldwide with the materials they need to advance scientific discovery.

Learn more about Deuterated Chemicals through,

• Deuterated Polymers: A Cornerstone Guide to Synthesis, Applications, and Future Trends
• Availability of All the Deuterated Chemicals at ResolveMass Laboratories Inc. 
• ResolveMass Laboratories: Leading Deuterated Chemical Synthesis Company in the United States.
• Deuterated Internal Standards for LC-MS: Selection & Custom Synthesis 
• How to Choose the Right Deuterated Labelled Chemical Synthesis Company in Canada 
• How to Choose the Right Deuterium Labelled Compounds Supplier for Your Lab 
• Deuterium-Labelled Compounds — Synthesis, Applications & Ordering 
• Custom Synthesis of Deuterated Chemicals