Deuterated 2-Vinylpyridine-α,β,β-d3 | CAS 352530-46-2

Deuterated 2-Vinylpyridine-α,β,β-d3 | CAS 352530-46-2 is a stable isotope-labeled analogue of 2-vinylpyridine in which three hydrogen atoms on the vinyl group are replaced with deuterium. This isotopic substitution preserves the chemical behavior of the parent compound while providing a distinct mass shift, making it highly valuable for mass spectrometry-based quantitative analysis, metabolic studies, analytical method development, and isotope dilution experiments. The deuterium atoms are located specifically at the α,β,β positions of the vinyl group, enabling accurate differentiation from the non-labeled compound during LC-MS and GC-MS analyses.

At ResolveMass Laboratories Inc., our deuterated reference standards are manufactured to meet the stringent quality requirements of pharmaceutical, biotechnology, environmental, forensic, and academic research laboratories. Each batch is produced under rigorous quality control to ensure high isotopic enrichment, excellent chemical purity, and reliable analytical performance.

Chemical Properties

Applications

Deuterated 2-Vinylpyridine-α,β,β-d3 is widely used as an internal standard for quantitative mass spectrometric analysis. Because the labeled compound exhibits nearly identical chromatographic behavior to the native analyte while producing a distinguishable mass spectrum, it significantly improves analytical accuracy and precision.

Pharmaceutical Research

The compound is extensively employed during pharmaceutical development for analytical method validation, impurity profiling, pharmacokinetic investigations, and bioanalytical assay development. Stable isotope-labeled standards help compensate for matrix effects, extraction variability, and instrument fluctuations, resulting in more reproducible quantitative data.

LC-MS and GC-MS Internal Standard

Modern analytical laboratories rely on isotope-labeled internal standards to achieve accurate quantification. Deuterated 2-Vinylpyridine-α,β,β-d3 serves as an ideal internal standard because it co-elutes with the unlabeled analyte while remaining distinguishable by its increased molecular mass. This improves sensitivity, precision, and reproducibility in complex biological and environmental matrices.

Method Development and Validation

Analytical scientists use this compound during method optimization and validation according to international regulatory guidelines. It supports the evaluation of method precision, recovery, accuracy, linearity, robustness, and detection limits for chromatographic and mass spectrometric methods.

Metabolic and Isotope Tracing Studies

Stable isotope labeling enables researchers to investigate chemical transformations and metabolic pathways without altering the compound’s intrinsic chemical properties. The deuterium label facilitates tracking during metabolic experiments and mechanistic investigations while minimizing interference from endogenous compounds.

Environmental and Industrial Analysis

Deuterated vinyl pyridine standards are also useful in environmental monitoring and industrial chemical analysis where accurate quantification of pyridine derivatives is required. Their use improves confidence in trace-level measurements across diverse sample matrices.

Advantages of Deuterated 2-Vinylpyridine-α,β,β-d3

Researchers prefer stable isotope-labeled compounds because they provide several analytical benefits:

• High isotopic enrichment for reliable mass spectrometric detection.
• Improved quantitative accuracy through isotope dilution methodology.
• Excellent chromatographic matching with the native compound.
• Compensation for sample preparation losses and ionization variability.
• Enhanced reproducibility across different analytical instruments.
• Suitable for highly sensitive LC-MS/MS and GC-MS workflows.
• Supports regulatory-compliant analytical method validation.

These characteristics make Deuterated 2-Vinylpyridine-α,β,β-d3 an essential analytical reference material for laboratories performing high-precision quantitative measurements.

Quality Assurance

ResolveMass Laboratories Inc. is committed to supplying isotope-labeled compounds that meet demanding research and analytical requirements. Every production batch undergoes comprehensive quality assessment, including identity verification, isotopic enrichment confirmation, and purity evaluation using advanced analytical techniques.

Our quality control procedures help ensure batch-to-batch consistency, allowing researchers to generate reproducible and reliable analytical data throughout their studies.

Storage and Handling

For optimal long-term stability, Deuterated 2-Vinylpyridine-α,β,β-d3 should be stored in tightly sealed containers under recommended laboratory storage conditions. The material should be protected from excessive heat, moisture, light, and strong oxidizing agents. Appropriate laboratory safety practices should always be followed when handling isotope-labeled organic compounds.

Why Choose ResolveMass Laboratories Inc.?

ResolveMass Laboratories Inc. specializes in supplying premium stable isotope-labeled standards for pharmaceutical, biotechnology, clinical, environmental, and research applications. Our products are developed to support scientists working in analytical chemistry, bioanalysis, drug development, and regulatory testing.

Customers choose ResolveMass because of our:

• High-purity isotope-labeled compounds.
• Reliable isotopic enrichment.
• Strict quality control and analytical verification.
• Consistent batch-to-batch performance.
• Global supply capabilities.
• Technical expertise in stable isotope chemistry.
• Dedicated customer support for research and pharmaceutical applications.

Whether you are developing quantitative LC-MS/MS methods, validating analytical procedures, conducting pharmacokinetic studies, or performing isotope dilution analyses, Deuterated 2-Vinylpyridine-α,β,β-d3 provides the analytical reliability required for high-quality scientific research.

For additional technical information, product specifications, or custom isotope-labeled compounds, contact ResolveMass Laboratories Inc. Our experienced team is committed to delivering high-quality stable isotope standards that support accurate, reproducible, and regulatory-compliant analytical workflows.

Learn more about Deuterated Chemicals through,

• Deuterated Polymers: A Cornerstone Guide to Synthesis, Applications, and Future Trends
• Availability of All the Deuterated Chemicals at ResolveMass Laboratories Inc. 
• ResolveMass Laboratories: Leading Deuterated Chemical Synthesis Company in the United States.
• Deuterated Internal Standards for LC-MS: Selection & Custom Synthesis 
• How to Choose the Right Deuterated Labelled Chemical Synthesis Company in Canada 
• How to Choose the Right Deuterium Labelled Compounds Supplier for Your Lab 
• Deuterium-Labelled Compounds — Synthesis, Applications & Ordering 
• Custom Synthesis of Deuterated Chemicals