Deuterated Dichlorodimethylsilane-d6 | CAS 80311-36-0

Deuterated Dichlorodimethylsilane-d6 | CAS 80311-36-0

Deuterated Dichlorodimethylsilane-d6 | CAS 80311-36-0 is a stable isotope-labeled organosilicon compound in which all six hydrogen atoms of the two methyl groups are replaced with deuterium (²H). With the molecular formula C₂Cl₂D₆Si and a molecular weight of 135.10 g/mol, this highly specialized reagent plays an important role in isotope labeling, silicon chemistry research, analytical method development, and the synthesis of deuterated silicon-containing compounds.

At ResolveMass Laboratories Inc., we provide high-quality Deuterated Dichlorodimethylsilane-d6 for pharmaceutical, chemical, materials science, and academic research applications. Our isotope-labeled compounds are manufactured and supplied with stringent quality standards to support laboratories requiring reliable deuterated reagents for advanced analytical and synthetic research.

Product Information

• Product Name: Deuterated Dichlorodimethylsilane-d6
• CAS Number: 80311-36-0
• Molecular Formula: C₂Cl₂D₆Si
• Molecular Weight: 135.10 g/mol
• Chemical Class: Deuterated Organosilicon Compound
• Synonyms: Dichlorodimethyl-d6-silane, Bis(trideuteromethyl)dichlorosilane
• Application: Isotope labeling, silicon chemistry, analytical standards, specialty synthesis

What is Deuterated Dichlorodimethylsilane-d6?

Deuterated Dichlorodimethylsilane-d6 is the isotopically labeled analogue of dichlorodimethylsilane, one of the most widely used intermediates in organosilicon chemistry. In this compound, the two methyl groups contain deuterium atoms instead of hydrogen, allowing scientists to distinguish the molecule during analytical studies without significantly altering its chemical behavior.

Because deuterium behaves chemically similar to hydrogen while exhibiting a different atomic mass, this compound is particularly valuable in mass spectrometry, isotope tracing experiments, mechanistic investigations, and spectroscopic studies.

The silicon center contains two reactive chlorine atoms, making the molecule an excellent precursor for producing deuterated silanes, siloxanes, silicone derivatives, and other silicon-based specialty materials.

Applications of Deuterated Dichlorodimethylsilane-d6

Stable Isotope Labeling

One of the primary uses of this compound is the preparation of isotope-labeled silicon-containing molecules. Researchers synthesize deuterated analogues to investigate reaction mechanisms, degradation pathways, and molecular transformations while maintaining nearly identical chemical properties to the unlabeled compound.

Stable isotope labeling provides higher confidence in analytical studies because deuterated compounds can be easily differentiated using mass spectrometry.

Mass Spectrometry Method Development

Modern LC-MS and GC-MS methods frequently utilize deuterated compounds as internal standards or reference materials.

Although Deuterated Dichlorodimethylsilane-d6 is generally used as a synthetic intermediate rather than a direct analytical standard, it enables preparation of isotope-labeled silicon-containing molecules used for:

• Quantitative LC-MS analysis
• GC-MS calibration
• Analytical method validation
• Instrument qualification
• Recovery studies
• Matrix effect evaluation

Its predictable isotopic mass shift simplifies identification during mass spectral analysis.

Silicon Chemistry Research

Organosilicon compounds remain important in pharmaceuticals, polymers, electronics, and advanced materials.

Researchers use Deuterated Dichlorodimethylsilane-d6 for studying:

• Silicon-carbon bond formation
• Silicon substitution reactions
• Organosilicon reaction mechanisms
• Chlorosilane chemistry
• Hydrolysis pathways
• Siloxane formation

Because deuterium labeling does not substantially change chemical reactivity, researchers can accurately investigate kinetic isotope effects and mechanistic pathways.

Synthesis of Deuterated Siloxanes

Siloxanes are widely used in medical devices, coatings, elastomers, adhesives, and specialty polymers.

Deuterated Dichlorodimethylsilane-d6 serves as an important building block for preparing:

• Deuterated silicone oils
• Labeled siloxane oligomers
• Silicone reference materials
• Research-grade silicone polymers
• Isotope-labeled organosilicon intermediates

These materials are valuable in both industrial R&D and analytical laboratories.

Spectroscopic Research

The replacement of hydrogen with deuterium changes vibrational frequencies, making isotope-labeled compounds useful for spectroscopy.

Researchers employ Deuterated Dichlorodimethylsilane-d6 in:

• NMR investigations
• IR spectroscopy
• Raman spectroscopy
• Vibrational analysis
• Structural characterization

The compound assists scientists in assigning molecular vibrations and understanding silicon-based molecular structures.

Benefits of Using Deuterated Dichlorodimethylsilane-d6

High Isotopic Purity

Reliable isotope incorporation is essential for analytical accuracy. High isotopic enrichment minimizes interference from non-deuterated species and improves reproducibility.

Excellent Synthetic Intermediate

The reactive chlorosilane functionality enables efficient synthesis of a wide variety of labeled organosilicon compounds.

Improved Mass Spectrometric Identification

The predictable mass increase resulting from deuterium incorporation allows rapid differentiation between labeled and unlabeled molecules during LC-MS and GC-MS analysis.

Supports Mechanistic Studies

Scientists investigating silicon chemistry benefit from isotope labeling because deuterium provides additional insight into reaction pathways and kinetic behavior.

Versatile Research Reagent

The compound is suitable for pharmaceutical research, polymer chemistry, materials science, analytical chemistry, and academic investigations.

Typical Research Applications

Deuterated Dichlorodimethylsilane-d6 is commonly used in:

• Stable isotope labeling
• Pharmaceutical research
• Analytical chemistry
• Organosilicon synthesis
• Polymer research
• Silicone material development
• Mass spectrometry
• LC-MS method development
• GC-MS calibration
• Academic research
• Chemical reference material preparation
• Reaction mechanism studies

Why Choose ResolveMass Laboratories Inc.?

ResolveMass Laboratories Inc. supplies premium-quality stable isotope-labeled compounds to support pharmaceutical, biotechnology, environmental, forensic, and academic research laboratories worldwide.

Our deuterated reference materials are manufactured with an emphasis on:

• High isotopic enrichment
• Consistent batch-to-batch quality
• Comprehensive analytical characterization
• Reliable documentation
• Research-grade purity
• Expert technical support
• Global supply capabilities

Whether your project involves analytical method development, isotope labeling, or advanced organosilicon synthesis, our team is committed to providing dependable deuterated compounds that meet the rigorous requirements of modern research laboratories.

Learn more about Deuterated Chemicals through,

• Deuterated Polymers: A Cornerstone Guide to Synthesis, Applications, and Future Trends
• Availability of All the Deuterated Chemicals at ResolveMass Laboratories Inc. 
• ResolveMass Laboratories: Leading Deuterated Chemical Synthesis Company in the United States.
• Deuterated Internal Standards for LC-MS: Selection & Custom Synthesis 
• How to Choose the Right Deuterated Labelled Chemical Synthesis Company in Canada 
• How to Choose the Right Deuterium Labelled Compounds Supplier for Your Lab 
• Deuterium-Labelled Compounds — Synthesis, Applications & Ordering 
• Custom Synthesis of Deuterated Chemicals