Deuterated Epichlorohydrin-d2 | CAS 69533-54-6

PRODUCT OVERVIEW

Deuterated Epichlorohydrin-d2 | CAS 69533-54-6  is a high-purity, isotopically labeled analogue of epichlorohydrin in which two hydrogen atoms have been replaced by deuterium atoms (²H or D). This deuterium incorporation confers distinct mass spectral signatures and altered vibrational properties, making the compound invaluable in analytical chemistry and mass spectrometry applications.

As a specialized stable isotope reagent, Deuterated Epichlorohydrin-d2 is predominantly used as an internal standard, calibration reference, or tracer for quantitative analyses where accuracy and reproducibility are critical.

CHEMICAL INFORMATION

• Name: Deuterated Epichlorohydrin-d2

• CAS Number: 69533-54-6

• Molecular Formula: C₃H₄D₂Cl₂O

• Molecular Weight: 94.53 Da

• Purity: Typically ≥98% (isotope and chemical purity, validated by NMR and MS)

• Isotopic Enrichment: High deuterium incorporation confirmed by spectroscopic analysis

ResolveMass Laboratories Inc. provides Deuterated Epichlorohydrin-d2 with rigorous quality control, ensuring batch-to-batch consistency and certificate of analysis documentation for traceability.

KEY FEATURES & BENEFITS

High Isotopic Purity – Precisely deuterated positions enhance quantitation accuracy while minimizing interference with native analyte signals.

Analytical Versatility – Serves as an ideal internal standard for mass spectrometry, providing stable reference peaks with minimal overlap in complex matrices.

Chromatographic Compatibility – Suitable for use in GC-MS and LC-MS workflows due to physicochemical similarity to unlabeled epichlorohydrin with predictable retention behavior.

Spectroscopic Distinction – Deuterium shifts in NMR and IR spectra enable unambiguous peak assignments and mechanistic studies.

Research Grade Quality – Supplied with detailed QC data, including NMR, MS, and isotopic enrichment metrics to support high-confidence research and regulatory compliance.

APPLICATIONS  of  Deuterated Epichlorohydrin-d2 | CAS 69533-54-6 

Mass Spectrometry Internal Standard

In quantitative GC-MS and LC-MS analyses, Deuterated Epichlorohydrin-d2 serves as an internal standard to correct for analytical variability, ion suppression, and instrumental drift. Its mass shift relative to the unlabeled compound allows for precise quantitation in environmental, pharmaceutical, and forensic testing.

Metabolic Tracing

The deuterated molecule is a useful tracer in metabolic and kinetic experiments where stable isotope labeling enables tracking of reaction pathways and metabolite formation without radioactivity.

Structural Elucidation

Deuterium incorporation alters vibrational modes and chemical shifts in NMR and IR spectroscopy, improving interpretability in structural studies. This property is particularly valuable for complex mixtures or reaction intermediate characterization.

Method Development & Validation

Regulatory and quality laboratories often employ Deuterated Epichlorohydrin-d2 during method validation to establish limits of detection, quantification, and method precision. Its known response facilitates robust validation protocols.

Pharmaceutical and Chemical Research

Researchers investigating epoxide chemistry, polymer precursors, or synthesis pathways involving epichlorohydrin derivatives may use the deuterated form to probe reaction mechanisms and product distribution.

PHYSICAL & SPECTROSCOPIC PROPERTIES

Due to the presence of deuterium, the physical properties of Deuterated Epichlorohydrin-d2 closely resemble those of the non-labeled counterpart while exhibiting predictable isotopic shifts:

• NMR Characteristics: Distinct deuterium-substituted resonance patterns in ¹H and ²H NMR spectra.

• Mass Spectral Signature: Characteristic +2 Da mass shift relative to unlabeled epichlorohydrin, enabling clear differentiation.

• IR Absorption: Shifted C-D stretching frequencies compared to C-H, useful for vibrational analysis.

Comprehensive spectral data are provided with each lot for customer verification and method integration.

QUALITY ASSURANCE

ResolveMass Laboratories Inc. adheres to stringent quality control processes. Each batch of Deuterated Epichlorohydrin-d2 undergoes:

• ¹H and ²H NMR analysis for isotopic confirmation

• GC-MS or LC-MS verification for purity and identity

• Certificate of Analysis (CoA) issuance with lot-specific information

Our quality systems ensure that researchers, analytical labs, and industry professionals receive material that meets or exceeds expectations for critical applications.

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