Deuterated Epichlorohydrin-d5 | CAS 69533-54-6

PRODUCT OVERVIEW

Deuterated Epichlorohydrin-d5 | CAS 69533-54-6 is a high-purity isotopically labeled organic compound widely used in analytical chemistry, particularly in mass spectrometry, NMR spectroscopy, and tracer studies. As the fully deuterated analog of epichlorohydrin, it contains five deuterium atoms (d5), replacing five hydrogen atoms in the parent epichlorohydrin molecule. Its unique isotopic profile makes it an ideal internal standard and calibration reference for quantification and structure confirmation in complex matrices.

At ResolveMass Laboratories Inc., our Deuterated Epichlorohydrin-d5 is manufactured to the highest quality standards with stringent isotopic and chemical purity specifications. This ensures confidence in experimental reproducibility and data accuracy for research, pharmaceutical development, environmental monitoring, and forensic applications.

CHEMICAL IDENTIFICATION

• Name: Deuterated Epichlorohydrin-d5

• CAS Number: 69533-54-6

• Molecular Formula: C₃H₂D₅ClO

• Molecular Weight: 97.55 g/mol (exact mass varies by isotopic composition)

• Chemical Class: Deuterated epoxide and chlorinated organic compound

STRUCTURE & ISOTOPIC LABELING

Deuterated Epichlorohydrin-d5 retains the characteristic three-membered epoxide ring and the chloromethyl side chain of epichlorohydrin, but with selective substitution of deuterium (²H) for hydrogen (¹H). The incorporation of deuterium, a stable heavier isotope of hydrogen, imparts distinct mass spectral and spectroscopic features:

• Mass Spectrometry: The deuterium labels shift the molecular ion and fragment ions by predictable mass units, facilitating clear differentiation from unlabeled analytes.

• NMR Spectroscopy: Minimal proton signals are observed from the labeled positions, reducing spectral complexity and improving resolution of neighboring proton environments.

Together, these properties make Deuterated Epichlorohydrin-d5 an invaluable standard for quantitative mass spectrometry workflows and structural elucidation.

KEY FEATURES & BENEFITS

High Isotopic Purity

Our Deuterated Epichlorohydrin-d5 is synthesized under controlled conditions to maximize deuterium incorporation and minimize residual protium (¹H) content. High isotopic purity translates to:

• Accurate mass calibration in LC-MS and GC-MS assays.

• Reduced interference in quantification.

• Enhanced confidence in isotope dilution analysis.

Analytical Performance

As an internal standard, this compound provides:

• Stable, reproducible signal response.

• Consistent retention behavior in chromatographic systems.

• Reliable quantitation across diverse matrices (biological, environmental, industrial).

Structural Confirmation

In NMR and MS/MS applications, deuterium labeling assists in:

• Assigning fragmentation pathways.

• Distinguishing closely related structural isomers.

• Tracking metabolic or degradation pathways using isotopic tracing.

Chemical Stability

Deuterated Epichlorohydrin-d5 displays physical and chemical behaviors similar to its non-deuterated counterpart, including solubility and reactivity profiles, while offering the analytical distinction needed for labeled standards.

APPLICATIONS of  Deuterated Epichlorohydrin-d5 | CAS 69533-54-6

Deuterated Epichlorohydrin-d5 supports a wide range of scientific and industrial applications, particularly where precision and analytical rigor are paramount:

1. Mass Spectrometry Internal Standard

In quantitative mass spectrometric assays, Deuterated Epichlorohydrin-d5 serves as a robust internal standard. Its presence corrects for:

• Variability in sample processing.

• Ion suppression/enhancement effects.

• Instrument fluctuation across runs.

This leads to improved accuracy and precision in quantitation of epichlorohydrin or related compounds in complex samples.

2. Metabolic & Tracer Studies

Stable isotope labeling enables researchers to:

• Track metabolic fate in biological systems.

• Monitor chemical transformations in environmental studies.

• Investigate reaction mechanisms in synthetic chemistry.

Deuterated Epichlorohydrin-d5 can be incorporated into metabolic flux studies to reveal pathway dynamics.

3. NMR Spectroscopy

The deuterium label reduces background proton signals, resulting in:

• Cleaner spectra with less signal overlap.

• Enhanced visibility of target proton environments adjacent to labeled sites.

• Improved interpretation of structural and conformational data.

4. Quality Control & Method Validation

In regulated industries such as pharmaceuticals and food safety, Deuterated Epichlorohydrin-d5 is critical for:

• Method development and validation.

• Quantitation of trace impurities or degradation products.

• Compliance with analytical standards.

QUALITY & ASSURANCE

Our Deuterated Epichlorohydrin-d5 is produced in facilities that adhere to rigorous quality management systems. Each batch undergoes detailed analytical verification, including:

• Isotopic purity assessment (e.g., MS or NMR).

• Chemical purity evaluation by validated chromatography methods.

• Certificate of Analysis (CoA) accompanying each shipment with traceability and specification details.

These quality measures ensure that our deuterated standards meet the expectations of demanding analytical laboratories worldwide.

CUSTOMIZATION & SUPPORT

ResolveMass Laboratories Inc. offers technical support to help you integrate Deuterated Epichlorohydrin-d5 into your workflows. Custom isotopic labeling or concentration formulations may be available upon request to suit specialized applications.

Learn more about Deuterated Chemicals,

• Deuterated Polymers: A Cornerstone Guide to Synthesis, Applications, and Future Trends
• Availability of All the Deuterated Chemicals at ResolveMass Laboratories Inc. 
• ResolveMass Laboratories: Leading Deuterated Chemical Synthesis Company in the United States.
• Deuterated Internal Standards for LC-MS: Selection & Custom Synthesis 
• How to Choose the Right Deuterated Labelled Chemical Synthesis Company in Canada 
• How to Choose the Right Deuterium Labelled Compounds Supplier for Your Lab 
• Deuterium-Labelled Compounds — Synthesis, Applications & Ordering 
• Custom Synthesis of Deuterated Chemicals