OVERVIEW
Deuterated Ethyl-d3 acrylate | CAS 140-88-5 is a stable-isotope-labeled acrylate ester widely used in polymer research, reaction mechanism studies, NMR spectroscopy, and mass spectrometry experiments. As a deuterium-enriched analog of ethyl acrylate, this molecule incorporates three deuterium atoms (d3) in the ethyl group, enabling precise kinetic tracking, isotope dilution quantification, and mechanistic evaluation in both chemical and biochemical systems.
ResolveMass Laboratories Inc. supplies high-purity, research-grade Deuterated Ethyl-d3 Acrylate for advanced R&D programs in polymer chemistry, metabolomics, materials science, and analytical method development. With stringent quality control, chemical identity verification, and batch reproducibility, our product supports demanding academic and industrial applications.
CHEMICAL INFORMATION
Chemical Name: Deuterated Ethyl-d3 Acrylate
CAS Number: 140-88-5
Synonyms: Ethyl Acrylate-d3; Acrylate-d3 Ethyl Ester; Ethoxy-d3 Acrylate
Molecular Formula: C5H5D3O2
Molecular Weight: 103.14 g/mol
Structure Class: Deuterium-labeled acrylate ester
Isotope Labeling: Three deuterium atoms incorporated into the ethyl moiety
The substitution of deuterium for protium enhances molecular stability for spectroscopic study while minimally altering electronic structure, ensuring comparable reactivity and polymerization profiles relative to the unlabeled ester.
KEY FEATURES
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High chemical purity suitable for sensitive spectroscopic analysis
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Precisely defined isotopic enrichment (d3) for accurate quantification
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Compatible with free-radical, anionic, and controlled/living polymerization systems
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Excellent solvent compatibility (common organic solvents, acrylate monomer blends)
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Stable under recommended storage conditions with good shelf life
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Verified using NMR, GC-MS, and isotopic purity analysis
APPLICATIONS of Deuterated Ethyl-d3 acrylate | CAS 140-88-5
1. NMR and MS Spectroscopy
Deuterated Ethyl-d3 Acrylate is widely used as a stable isotope tracer for mechanistic and kinetic studies. Key advantages include:
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Clear isotopic separation in HRMS and LC–MS workflows
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Reduced spectral overlap in ¹H NMR due to replacement of hydrogens with deuterium
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Precision in quantitative isotope dilution and flux analysis
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Tracking acrylate ester transformation pathways
Its well-defined deuteration pattern makes it ideal for mass-balance studies, degradation tracking, and analytical method validation.
2. Polymer Chemistry & Material Science
Acrylate esters are foundational monomers in polymer and resin synthesis. The deuterated version enables:
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Mechanistic evaluation of polymerization kinetics
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Determination of chain-transfer constants and radical propagation rates
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Studying copolymer composition drift, monomer reactivity ratios, and microstructure
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Neutron scattering contrast variation, improving structural resolution in polymer blends and nanomaterials
Researchers use Deuterated Ethyl-d3 Acrylate to build deuterium-labeled polymer segments for structural elucidation using SANS/NR techniques.
3. Environmental and Biochemical Tracing
Isotope-labeled acrylates serve as powerful tracers in environmental and metabolic systems. Deuterated Ethyl-d3 Acrylate can support:
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Photochemical degradation pathway studies
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Tracking ester hydrolysis mechanisms
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Assessing environmental fate and polymer-derived microcontaminants
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Degradation monitoring in aqueous and biological systems
Stable isotope tracers help distinguish compound-derived signals from background organic matter.
4. Pharmaceutical & Biomedical Research
In drug-delivery and biomaterials research, deuterated acrylates assist in:
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Evaluating monomer migration, leaching behavior, and diffusivity
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Designing labeled polymeric excipients and hydrogels
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Polymer–drug interaction analysis within acrylate-based matrices
Such applications rely on the enhanced detectability provided by the deuterium mass shift.
TECHNICAL ADVANTAGES
High Isotopic Integrity
Consistent d3 labeling provides confident structural assignments and quantitative accuracy in isotope-dependent workflows.
Minimal Influence on Chemical Behavior
Deuterium retains similar electronegativity and steric characteristics to protium, ensuring analogous reactivity in polymerization and ester-based transformations.
Enhanced Analytical Resolution
The mass difference created by three deuterium atoms significantly improves peak separation in HRMS and facilitates isotope-pattern analysis.
Versatile Solubility
Compatible with organic solvent systems including THF, toluene, chloroform, DCM, acetonitrile, and common acrylate monomer blends.
QUALITY ASSURANCE
ResolveMass Laboratories Inc. ensures each batch of Deuterated Ethyl-d3 Acrylate undergoes:
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NMR (¹H, ²H, ¹³C) verification
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GC–MS and LC–MS identity and purity confirmation
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Isotopic enrichment assessment
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Residual solvents and moisture analysis
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Stabilizer/additive compatibility profiling
Our quality system supports reproducible performance for both academic and industrial R&D.
CONTACT US
If you require technical data, COA, pricing, or custom synthesis for deuterated monomers, our team is ready to assist.
For inquiries related to this product, please contact our scientific support team at ResolveMass Laboratories Inc.
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