Deuterated Ethylene Carbonate-d4 | CAS 362049-63-6

Deuterated Ethylene carbonate-d4 | CAS 362049-63-6 is a stable isotope-labelled analogue of ethylene carbonate in which four hydrogen atoms are replaced with deuterium (²H). This isotopically enriched compound exhibits nearly identical chemical and physical properties to native ethylene carbonate while providing a distinguishable mass shift during mass spectrometric analysis. Because of these characteristics, Ethylene Carbonate-d4 has become an indispensable analytical reference material for quantitative LC-MS/MS, GC-MS, isotope dilution analysis, pharmaceutical method validation, environmental monitoring, battery electrolyte research, and forensic investigations.

ResolveMass Laboratories Inc. supplies high-quality Deuterated Ethylene Carbonate-d4 manufactured under stringent quality standards to support pharmaceutical, chemical, environmental, and academic research laboratories worldwide. Each batch is carefully characterized to ensure high isotopic enrichment, exceptional chemical purity, and consistent analytical performance across demanding analytical workflows.

What is Deuterated Ethylene Carbonate-d4?

Ethylene carbonate is a cyclic organic carbonate widely used as a solvent and electrolyte component in lithium-ion batteries, polymer synthesis, specialty chemicals, and pharmaceutical manufacturing. The deuterated analogue retains the same molecular structure while replacing four hydrogen atoms with deuterium atoms, resulting in a predictable increase in molecular mass.

This isotopic substitution enables analytical scientists to differentiate the labelled compound from endogenous or sample-derived ethylene carbonate during mass spectrometric detection without significantly altering chromatographic retention or extraction behavior. As a result, Ethylene Carbonate-d4 serves as an ideal internal standard for accurate quantitative analysis.

Chemical Properties of Deuterated Ethylene Carbonate-d4

• Product Name: Deuterated Ethylene Carbonate-d4
• CAS Number: 362049-63-6
• Molecular Formula: C₃D₄O₃
• Molecular Weight: 92.08 g/mol
• Chemical Class: Cyclic organic carbonate
• Appearance: Colorless liquid or low-melting solid
• Isotopic Enrichment: Typically ≥98 atom % D

Applications of Deuterated Ethylene Carbonate-d4

LC-MS/MS Internal Standard

Ethylene Carbonate-d4 is widely employed as an internal standard during quantitative LC-MS/MS analysis. Because the labelled compound behaves nearly identically to the native analyte throughout extraction, chromatography, and ionization, it compensates for sample preparation losses, ion suppression, matrix effects, and instrument variability. This results in improved analytical precision and reproducibility.

GC-MS Quantification

The compound is equally valuable in gas chromatography-mass spectrometry (GC-MS) methods where precise quantification of ethylene carbonate is required. Stable isotope-labelled internal standards significantly improve method robustness while reducing analytical uncertainty.

Pharmaceutical Research

Pharmaceutical laboratories utilize Deuterated Ethylene Carbonate-d4 during analytical method development, validation, impurity profiling, forced degradation studies, extractables and leachables investigations, and quality control testing. Stable isotope-labelled standards are increasingly recommended for highly accurate quantitative pharmaceutical analyses.

Battery Electrolyte Research

Ethylene carbonate is one of the most important solvents used in lithium-ion battery electrolytes. Researchers studying electrolyte composition, degradation products, aging mechanisms, and solvent stability frequently employ Ethylene Carbonate-d4 as a tracer compound or calibration standard during LC-MS and GC-MS investigations.

Environmental Analysis

Industrial production and disposal of carbonate solvents have increased interest in environmental monitoring. Ethylene Carbonate-d4 supports accurate quantification of ethylene carbonate residues in wastewater, industrial emissions, environmental samples, and regulatory monitoring studies.

Chemical Manufacturing

Chemical manufacturers use isotope-labelled reference standards to validate analytical methods during process optimization, product quality verification, raw material analysis, and impurity monitoring.

Advantages of Using Deuterated Ethylene Carbonate-d4

Stable isotope-labelled internal standards provide numerous analytical benefits compared with external calibration methods.

Major advantages include:

• Excellent correction for matrix effects
• Improved quantitative accuracy
• Enhanced analytical precision
• Superior reproducibility across analytical batches
• Compensation for extraction losses
• Correction for sample preparation variability
• Improved calibration curve reliability
• Increased confidence during regulatory submissions
• Compatibility with LC-MS/MS and GC-MS workflows
• Reduced analytical bias

These advantages make Deuterated Ethylene Carbonate-d4 an essential reference material for laboratories requiring high-confidence quantitative measurements.

Quality Standards at ResolveMass Laboratories Inc.

ResolveMass Laboratories Inc. understands that isotope-labelled reference materials must deliver exceptional consistency for regulated analytical environments. Every batch of Deuterated Ethylene Carbonate-d4 undergoes comprehensive quality evaluation before release.

Quality testing typically includes:

• Identity confirmation
• Chemical purity assessment
• Isotopic enrichment verification
• Structural characterization
• Moisture evaluation where applicable
• Mass spectrometric verification
• Chromatographic purity analysis

This rigorous quality control ensures reliable analytical performance across pharmaceutical, chemical, and research applications.

Research Applications

Deuterated Ethylene Carbonate-d4 supports a wide variety of scientific disciplines, including:

• Pharmaceutical analytical chemistry
• Bioanalytical method development
• Stable isotope dilution assays
• LC-MS/MS quantification
• GC-MS method validation
• Chemical process development
• Environmental contaminant analysis
• Battery electrolyte characterization
• Polymer chemistry research
• Regulatory laboratory testing
• Academic research projects
• Industrial quality assurance

Its versatility makes it a valuable reference material across both regulated and exploratory analytical laboratories.

Why Choose ResolveMass Laboratories Inc.?

ResolveMass Laboratories Inc. is recognized for supplying premium stable isotope-labelled reference standards that meet the evolving needs of pharmaceutical, biotechnology, chemical, and academic laboratories. Our expertise in analytical chemistry and mass spectrometry allows us to deliver products that meet the highest standards of quality and reliability.

Customers benefit from:

• High-purity stable isotope-labelled compounds
• Consistent batch-to-batch quality
• Reliable analytical performance
• Comprehensive quality documentation
• Fast global shipping
• Technical support from experienced scientists
• Products suitable for research and method development
• Commitment to scientific excellence and customer satisfaction

Our isotope-labelled standards are trusted by laboratories performing highly sensitive quantitative analyses where analytical accuracy and reproducibility are essential.

Order Deuterated Ethylene Carbonate-d4

If your laboratory requires a dependable stable isotope-labelled reference standard for quantitative mass spectrometry, Deuterated Ethylene Carbonate-d4 (CAS 362049-63-6) from ResolveMass Laboratories Inc. provides the purity, isotopic integrity, and analytical reliability needed for advanced research and regulated laboratory applications.

Whether you are developing new analytical methods, validating pharmaceutical assays, studying lithium-ion battery electrolytes, or conducting environmental investigations, ResolveMass Laboratories Inc. offers high-quality isotope-labelled compounds designed to support accurate and reproducible scientific results.

Learn more about Deuterated Chemicals through,

• Deuterated Polymers: A Cornerstone Guide to Synthesis, Applications, and Future Trends
• Availability of All the Deuterated Chemicals at ResolveMass Laboratories Inc. 
• ResolveMass Laboratories: Leading Deuterated Chemical Synthesis Company in the United States.
• Deuterated Internal Standards for LC-MS: Selection & Custom Synthesis 
• How to Choose the Right Deuterated Labelled Chemical Synthesis Company in Canada 
• How to Choose the Right Deuterium Labelled Compounds Supplier for Your Lab 
• Deuterium-Labelled Compounds — Synthesis, Applications & Ordering 
• Custom Synthesis of Deuterated Chemicals