Deuterated Methacrylonitrile-d5 | CAS 32376-01-5

OVERVIEW
Deuterated Methacrylonitrile-d5 | CAS 32376-01-5 is a high-purity isotopically labeled chemical widely used in research applications, including mass spectrometry (MS), nuclear magnetic resonance (NMR), and isotopic tracing studies. The incorporation of deuterium atoms in the methacrylonitrile molecule provides distinct analytical advantages, enabling precise quantification, structural elucidation, and tracking of chemical reactions in complex systems.

At ResolveMass Laboratories Inc., we offer Deuterated Methacrylonitrile-d5 with exceptional isotopic purity and rigorous quality control, making it ideal for pharmaceutical research, polymer chemistry, and analytical method development.

CHEMICAL INFORMATION

• Chemical Name: Deuterated Methacrylonitrile-d5

• CAS Number: 32376-01-5

• Molecular Formula: C4D5N

• Molecular Weight: 72.12 g/mol (deuterated)

• Purity: ≥99% (typically specified by the lot)

• Deuteration Level: >98%

Deuterated Methacrylonitrile-d5 is structurally analogous to methacrylonitrile but with five hydrogen atoms replaced by deuterium. This isotopic substitution does not significantly alter the chemical reactivity but provides distinctive isotopic labeling, which is invaluable for mechanistic studies, kinetic isotope effect (KIE) experiments, and high-precision MS analyses.

APPLICATIONS  of  Deuterated Methacrylonitrile-d5 | CAS 32376-01-5

1. Analytical Chemistry and Mass Spectrometry:
   Deuterated Methacrylonitrile-d5 serves as an internal standard for LC-MS and GC-MS applications. Its isotopic labeling allows for accurate quantification of methacrylonitrile in complex matrices by providing a clear mass shift without affecting chromatographic behavior. Researchers rely on deuterated compounds to improve the reliability and reproducibility of quantitative analytical methods.

2. Nuclear Magnetic Resonance (NMR) Studies:
   In NMR spectroscopy, Deuterated Methacrylonitrile-d5 minimizes proton background signals, enhancing spectral clarity. It is used as a reference compound in proton-decoupled NMR experiments and for tracing molecular interactions in polymerization studies.

3. Polymer Chemistry:
   Methacrylonitrile derivatives are critical monomers in acrylic and methacrylic polymer formulations. Deuterated Methacrylonitrile-d5 enables researchers to study polymerization kinetics, monitor monomer conversion, and track isotopic incorporation within polymer chains, providing insights into reaction mechanisms and polymer microstructure.

4. Pharmaceutical and Isotopic Research:
   Isotopically labeled compounds, including Deuterated Methacrylonitrile-d5, are used in drug metabolism and pharmacokinetic studies to trace the distribution and transformation of chemical entities in biological systems. The deuterium label allows differentiation between the administered compound and endogenous metabolites.

5. Mechanistic and Kinetic Studies:
   The substitution of hydrogen with deuterium allows scientists to investigate kinetic isotope effects, providing mechanistic insights into chemical reactions. Deuterated Methacrylonitrile-d5 is essential for studies involving hydrogen abstraction, radical reactions, and catalytic processes.

QUALITY CONTROL AND CERTIFICATION
At ResolveMass Laboratories Inc., each batch of Deuterated Methacrylonitrile-d5 undergoes rigorous quality control to ensure isotopic purity, chemical integrity, and lot-to-lot consistency. Analytical techniques employed include:

• Proton and deuterium NMR spectroscopy

• Gas chromatography–mass spectrometry (GC-MS)

• High-performance liquid chromatography (HPLC)

Our ISO-compliant processes guarantee that our deuterated chemicals meet the highest standards for research applications.

WHY CHOOSE RESOLVEMASS LABORATORIES INC.
ResolveMass Laboratories Inc. is committed to providing premium isotopically labeled compounds with unmatched reliability. Researchers and industry professionals trust our products for their precision, purity, and consistency. We offer flexible packaging options, technical support, and detailed documentation to support your research and development goals.

CONCLUSION
Deuterated Methacrylonitrile-d5 (CAS 32376-01-5) is an indispensable tool for modern analytical chemistry, polymer research, and pharmaceutical studies. Its high isotopic purity and well-characterized properties make it ideal for mass spectrometry, NMR, polymerization studies, and isotopic tracing experiments. ResolveMass Laboratories Inc. ensures that each product meets stringent quality standards, supporting reliable and reproducible scientific research.

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