Deuterated Styrene-d8 | CAS 19361-62-7

OVERVIEW

Deuterated Styrene-d8 | CAS 19361-62-7  is a fully deuterium-labeled analog of styrene in which all eight hydrogen atoms are replaced with deuterium (D), the stable heavy isotope of hydrogen. With the molecular formula C₈D₈ and molecular weight of approximately 112.20 g/mol, this isotopically enriched compound is widely used in analytical chemistry, mass spectrometry, polymer science, and mechanistic research.

Styrene-d8 maintains nearly identical chemical behavior to non-labeled styrene while offering a distinct mass shift of +8 amu. This isotopic differentiation makes it an essential reference material for isotope dilution methods, quantitative mass spectrometry, and advanced research applications. The compound is typically supplied as a high-purity, colorless liquid and may contain a trace polymerization inhibitor to enhance storage stability.

At ResolveMass Laboratories Inc., Deuterated Styrene-d8 is supplied with high isotopic enrichment and strict quality control to ensure reliable performance in analytical and research environments.

CHEMICAL INFORMATION

• Chemical Name: Styrene-d8

• CAS Number: 19361-62-7

• Molecular Formula: C₈D₈

• Molecular Weight: 112.20 g/mol

• Structure: Fully deuterated vinylbenzene

• Appearance: Clear to colorless liquid

• Isotopic Purity: Typically ≥98 atom % D

• Chemical Purity: ≥98% (GC)

Styrene-d8 shares similar physical and chemical properties with unlabeled styrene, including volatility and polymerization behavior. Due to its vinyl functional group, it can undergo free-radical polymerization; therefore, proper storage conditions are essential to maintain stability.

APPLICATIONS  of  Deuterated Styrene-d8 | CAS 19361-62-7

1. Mass Spectrometry Internal Standard

Deuterated Styrene-d8 is widely used as an internal standard in GC-MS and LC-MS analysis of styrene and related volatile organic compounds (VOCs). Because its chemical properties closely match native styrene, it behaves identically during sample preparation and chromatographic separation. However, its +8 mass unit shift allows clear differentiation in the mass spectrometer, enabling accurate quantification even in complex matrices.

This makes Styrene-d8 particularly valuable for:

• Environmental VOC analysis

• Industrial hygiene monitoring

• Petrochemical analysis

• Residual monomer quantification

• Method validation and calibration

2. Isotope Dilution Mass Spectrometry (IDMS)

In isotope dilution workflows, Styrene-d8 improves analytical accuracy by compensating for matrix effects, recovery losses, and instrument variability. Because the labeled compound co-elutes with the analyte of interest, it serves as a highly reliable quantitative reference. Laboratories performing trace-level analysis benefit from enhanced precision and reproducibility.

3. Polymer & Materials Research

Styrene-d8 can be polymerized to produce deuterated polystyrene, which is used in advanced materials research. Deuterated polymers are particularly useful in:

• Neutron scattering experiments

• NMR spectroscopy studies

• Polymer dynamics research

• Interfacial and thin-film analysis

The isotopic substitution modifies vibrational modes without significantly altering chemical behavior, making it a powerful tool for structural and mechanistic investigations.

4. Reaction Mechanism & Kinetic Studies

Deuterium substitution allows researchers to investigate kinetic isotope effects (KIE) and reaction pathways. By comparing reaction rates between styrene and styrene-d8, scientists can gain insights into bond-breaking processes and catalytic mechanisms. This makes the compound valuable in academic and industrial R&D settings.

QUALITY & PERFORMANCE

ResolveMass Laboratories Inc. provides Deuterated Styrene-d8 manufactured and tested to meet high analytical standards. Each batch is quality-verified for:

• Isotopic enrichment

• Chemical purity

• Identity confirmation

• Stability

The product is suitable for research, analytical method development, and regulated laboratory environments where reproducibility and traceability are critical.

WHY CHOOSE RESOLVEMASS LABORATORIES INC.

At ResolveMass Laboratories Inc., we specialize in high-quality isotopically labeled standards tailored for advanced analytical and research applications. Our Deuterated Styrene-d8 is supplied with:

• High isotopic purity

• Reliable batch-to-batch consistency

• Technical support from experienced scientists

• Custom solutions for specialized applications

Whether you are developing a quantitative mass spectrometry method, validating analytical procedures, or conducting polymer research, our isotopically labeled standards are designed to deliver accuracy, precision, and performance.

Learn more about Deuterated Chemicals through,

• Deuterated Polymers: A Cornerstone Guide to Synthesis, Applications, and Future Trends
• Availability of All the Deuterated Chemicals at ResolveMass Laboratories Inc. 
• ResolveMass Laboratories: Leading Deuterated Chemical Synthesis Company in the United States.
• Deuterated Internal Standards for LC-MS: Selection & Custom Synthesis 
• How to Choose the Right Deuterated Labelled Chemical Synthesis Company in Canada 
• How to Choose the Right Deuterium Labelled Compounds Supplier for Your Lab 
• Deuterium-Labelled Compounds — Synthesis, Applications & Ordering 
• Custom Synthesis of Deuterated Chemicals