OVERVIEW
Deuterated tert-Butyl Methacrylate-d14 (t-BMA-d14) is a fully deuterium-labeled derivative of tert-butyl methacrylate in which the tert-butyl functional group contains 14 deuterium atoms. This isotopically enriched monomer is widely used in advanced polymer research, reaction mechanism studies, kinetic isotope investigations, and high-precision analytical applications. Because of its heavy hydrogen substitution, t-BMA-d14 provides distinctive spectral signatures in NMR, MS, and IR, enabling clearer interpretation of polymerization pathways, chain-end structures, and degradation mechanisms.
ResolveMass Laboratories Inc. supplies high-purity, research-grade t-BMA-d14 suitable for academic laboratories, analytical R&D facilities, polymer science groups, and formulation scientists working toward next-generation isotopic materials.
CHEMICAL INFORMATION
• Chemical Name: tert-Butyl Methacrylate-d14
• Synonyms: t-BMA-d14, TBMA-d14, Deuterated tert-butyl methacrylate
• Isotopic Labeling: 99–99.5% D incorporation (typical)
• Molecular Formula: C₈D₁₄O₂
• Key Functional Groups: Methacrylate vinyl group, deuterated tert-butyl ester
• Structural Feature: The methyl and methylene hydrogens of the tert-butyl moiety are replaced with deuterium, offering strong isotopic contrast for mechanistic and analytical tracing.
The heavy deuteration significantly influences the vibrational, rotational, and magnetic properties of the molecule, making the compound ideal for mechanistic elucidation, kinetic interpretation, and polymer structure confirmation.
FEATURES & BENEFITS
High Deuterium Purity:
The fully labeled tert-butyl group produces well-separated peaks in NMR, allowing scientists to confidently track monomer integration into polymer chains.
Enhanced Spectral Resolution:
t-BMA-d14 is especially valuable in ¹H-NMR suppression studies, ²H-NMR experiments, and MS-based tracing due to its appreciable mass shift and reduced proton background.
Mechanistic Insights in Polymerization:
The deuterium isotope effect modifies reaction kinetics in predictable ways. By comparing polymerization behavior between protio-TBMA and d14-TBMA, researchers can extract fundamental information about radical propagation, termination, and chain transfer events.
Stability and Ease of Handling:
The tert-butyl ester group provides steric bulk and improved hydrolytic stability compared with many alternative methacrylate monomers, while deuteration does not compromise chemical robustness.
APPLICATIONS of Deuterated tert-Butyl methacrylate-d14
1. Polymerization Mechanism Studies:
t-BMA-d14 is widely used in free-radical, RAFT, ATRP, and anionic polymerization research to evaluate monomer reactivity, propagation pathways, and end-group fidelity. Deuterium substitution allows researchers to differentiate polymer chain segments by NMR or mass spectrometry with extraordinary clarity.
2. Kinetic Isotope Effect (KIE) Investigations:
Deuterium significantly alters C–D bond vibrational energy and affects reaction rates. Scientists employ t-BMA-d14 to understand rate-determining steps, activation energy differences, chain transfer phenomena, and thermo-chemical behavior.
3. Structural Elucidation of Polymers:
Multinuclear NMR (¹H-decoupled ²H-NMR, ¹³C-NMR with isotopic shifts) becomes more informative when deuterated monomers are incorporated. This enables accurate mapping of polymer composition, sequence distribution, branching, block formation, or copolymer arrangement.
4. Mass Spectrometry Tracing:
The +14 mass increase compared to non-deuterated TBMA offers unambiguous markers in MALDI-TOF, ESI-MS, and LC–MS polymer fingerprinting studies. Researchers use this to track degradation pathways, oligomer distribution, and reaction intermediates.
5. Reference Material for Analytical Calibration:
t-BMA-d14 serves as a valuable internal standard for analytical methods requiring isotopic differentiation, particularly in polymer quantification, impurity profiling, and decomposition product analysis.
6. Model Monomer in Material Science:
The tert-butyl methacrylate backbone is common in specialty coatings, adhesives, responsive hydrogels, and advanced composites. Deuterated versions allow scientists to investigate polymer mobility, segmental behavior, and cross-linking density by neutron scattering and solid-state NMR.
QUALITY & COMPLIANCE
ResolveMass Laboratories Inc. provides deuterated tert-butyl methacrylate-d14 with stringent quality control, verified isotopic purity, and batch-specific analytical documentation. Each lot undergoes NMR validation, GC purity testing, and moisture analysis to ensure optimal performance in sensitive analytical and mechanistic research applications.
STORAGE & STABILITY
We recommend storing t-BMA-d14 in a tightly sealed container, under inert atmosphere when possible, and at low temperature (2–8°C). Protect the monomer from light and moisture to maintain its stability and prevent unwanted polymerization.
WHY CHOOSE RESOLVEMASS LABORATORIES INC.
ResolveMass Laboratories Inc. specializes in high-purity isotopically labeled chemicals, supporting academic researchers, pharmaceutical innovators, materials scientists, and advanced polymer R&D teams. Our products are backed by technical expertise, comprehensive documentation, and responsive scientific support for both small-scale research and large-volume projects.
Learn more through,
Deuterated Polymers: A Cornerstone Guide to Synthesis, Applications, and Future Trends
Availability of All the Deuterated Chemicals at ResolveMass Laboratories Inc.
ResolveMass Laboratories: Leading Deuterated Chemical Synthesis Company in the United States.
Deuterated Internal Standards for LC-MS: Selection & Custom Synthesis
How to Choose the Right Deuterated Labelled Chemical Synthesis Company in Canada
How to Choose the Right Deuterium Labelled Compounds Supplier for Your Lab
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Custom Synthesis of Deuterated Chemicals
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