Deuterated Trifluoroethyl methacrylate-d5

OVERVIEW

Deuterated Trifluoroethyl methacrylate-d5 is a highly specialized, isotopically labeled methacrylate monomer engineered for advanced polymer research, analytical method development, and mechanistic studies involving fluorinated acrylic systems. By incorporating five deuterium atoms in place of protium, TFEMA-d5 provides exceptional analytical clarity in NMR, MS, and isotopic tracing applications while maintaining the reactive methacrylate functionality crucial for controlled radical polymerization.

This deuterated monomer is widely used in the synthesis of fluorinated, high-performance specialty polymers—including hydrophobic coatings, dielectric materials, membrane systems, and traceable co-polymers for structural elucidation studies. Researchers rely on TFEMA-d5 for its excellent stability, clean isotopic labeling pattern, and compatibility with RAFT, ATRP, and free-radical polymerization systems.

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CHEMICAL INFORMATION

• Chemical Name: Deuterated Trifluoroethyl Methacrylate-d5

• Synonyms: TFEMA-d5, TFEM-d5, 2,2,2-Trifluoroethyl Methacrylate-d5

• Isotopic Labeling: Five deuterium atoms (≥98% D)

• Functional Group: Methacrylate ester

• Physical Form: Clear to slightly yellow liquid

• Typical Purity: ≥98%

• Reactivity: Polymerizable vinyl monomer

The deuterium incorporation enhances mass spectral resolution and reduces proton interference in NMR, allowing highly accurate structural and quantitative analyses of copolymers, degradation by-products, and polymerization kinetics.

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KEY FEATURES & BENEFITS

High Isotopic Purity

TFEMA-d5 is manufactured with a high deuterium incorporation level, ensuring sharp mass spectral peaks and reduced background noise in proton-based spectroscopic techniques. This allows researchers to confidently track polymer behavior, reaction intermediates, and degradation pathways.

Fully Polymerizable Methacrylate Group

Despite isotopic labeling, TFEMA-d5 maintains the same reactivity profile as non-deuterated TFEMA. This ensures compatibility with established polymerization systems and predictable copolymer incorporation without altering kinetics.

Enhanced Analytical Traceability

The presence of five deuterium atoms provides a distinct isotopic signature. This is especially valuable in:

• Copolymer composition profiling

• Monitoring monomer conversion

• Studying mass transport within polymer matrices

• Degradation and fragmentation analysis

• Labeling for quantitative multi-omics or surface-interaction studies

Excellent Chemical Stability

The trifluoroethyl ester imparts chemical robustness and hydrophobicity, while deuteration enhances resistance to certain chemical exchange processes, making it ideal for long-term analytical studies.

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APPLICATIONS

Polymer Research & Development

TFEMA-d5 serves as a powerful monomer for synthesizing fluorinated, isotopically labeled polymers and copolymers used in:

• High-performance coatings

• Hydrophobic and oleophobic surfaces

• Optical and dielectric materials

• Specialty elastomers

Its fluorinated backbone contributes to chemical resistance, low surface energy, and improved mechanical durability.

Mechanistic Studies in Polymer Chemistry

Researchers use TFEMA-d5 to gain deeper insights into polymerization processes, including:

• Reaction pathway elucidation

• Chain-transfer behavior

• RAFT or ATRP kinetic profiling

• End-group fidelity in controlled polymerization

Deuteration enables selective tracking of the monomer during polymer growth and post-polymerization chemical modifications.

NMR and Mass Spectrometry Tracing

The molecule’s clean isotopic pattern makes it ideal for high-precision analytical workflows such as:

• ^1H NMR suppression studies

• ^2H NMR quantification

• Stable-isotope mass spectrometry

• Degradation profiling of fluorinated polymers

Material Science & Surface Engineering

When incorporated into polymer networks, the trifluoroethyl group enhances hydrophobicity and surface repellency. This makes TFEMA-d5 useful for creating labeled versions of:

• Water-resistant coatings

• Anti-smudge films

• Membrane materials

• High-frequency electronics components

Environmental Fate & Degradation Research

Fluorinated polymers often require detailed degradation studies. Incorporating deuterium enables clearer detection of fragmentation pathways and environmental transformation products.

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HANDLING & STORAGE

• Store under inert gas such as nitrogen or argon.

• Keep in a cool, dry place away from light.

• Avoid elevated temperatures to prevent unwanted polymerization.

• Use standard precautions for handling reactive vinyl monomers.

• Consider adding polymerization inhibitors if long-term storage is required.

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WHY CHOOSE RESOLVEMASS LABORATORIES INC.

ResolveMass Laboratories Inc. specializes in high-purity, isotopically labeled chemicals for advanced R&D applications. All batches of TFEMA-d5 undergo rigorous characterization using NMR, MS, GC, and Karl Fischer moisture testing to guarantee excellent purity, isotopic consistency, and performance in sensitive analytical workflows.

 

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