PRODUCT OVERVIEW
ethyl 4-oxo-3,4-dihydrophthalazine-1-carboxylate | CAS 23952-05-8 is a specialized chemical intermediate widely used in pharmaceutical and chemical research applications. This compound belongs to the class of phthalazine derivatives, which are known for their versatile reactivity and potential in medicinal chemistry. Its structural framework, featuring a fused heterocyclic phthalazine ring and an ester functional group, provides multiple opportunities for chemical modification, making it valuable in the synthesis of bioactive molecules, drug candidates, and heterocyclic intermediates.
At ResolveMass Laboratories Inc., we provide high-purity ethyl 4-oxo-3,4-dihydrophthalazine-1-carboxylate, suitable for both research and development applications. Our product is manufactured under strict quality control standards, ensuring batch-to-batch consistency, analytical reliability, and compliance with international laboratory requirements.
CHEMICAL INFORMATION
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IUPAC Name: Ethyl 4-oxo-3,4-dihydrophthalazine-1-carboxylate
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CAS Number: 23952-05-8
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Molecular Formula: C10H10N2O3
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Molecular Weight: 218.21 g/mol
SYNTHESIS AND CHEMICAL REACTIVITY
Ethyl 4-oxo-3,4-dihydrophthalazine-1-carboxylate is commonly synthesized through the condensation of phthalic anhydride derivatives with hydrazine, followed by esterification. Its keto and ester functionalities enable participation in various chemical reactions, including:
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Nucleophilic substitution at the ester group
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Cyclization reactions to generate fused heterocycles
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Reduction or derivatization of the ketone for drug discovery applications
Due to its reactive nature, this compound serves as a key intermediate in the synthesis of therapeutic molecules, particularly in the fields of cardiovascular, anti-inflammatory, and central nervous system (CNS) drug development.
APPLICATIONS IN RESEARCH AND INDUSTRY of ethyl 4-oxo-3,4-dihydrophthalazine-1-carboxylate | CAS 23952-05-8
Ethyl 4-oxo-3,4-dihydrophthalazine-1-carboxylate has a range of applications in medicinal chemistry, chemical biology, and pharmaceutical research. Key applications include:
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Drug Discovery & Development:
This compound is widely used as a precursor in the synthesis of phthalazine-based drug candidates, which exhibit activities such as anti-inflammatory, anti-cancer, and enzyme inhibition properties. -
Chemical Intermediates for Heterocyclic Synthesis:
Its functional groups make it an ideal building block for creating complex heterocycles used in bioactive compound libraries. -
Pharmacological Screening:
Researchers often employ this compound in in vitro assays and structure-activity relationship (SAR) studies to evaluate potential biological activities of phthalazine derivatives. -
Custom Synthesis:
ResolveMass Laboratories Inc. can provide customized synthesis services using ethyl 4-oxo-3,4-dihydrophthalazine-1-carboxylate as a starting material, tailored for specific pharmaceutical applications.
SAFETY AND HANDLING
While ethyl 4-oxo-3,4-dihydrophthalazine-1-carboxylate is an important research chemical, proper laboratory handling is essential:
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Storage: Store in a cool, dry place, away from light and moisture.
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Protective Measures: Use standard personal protective equipment (PPE) such as gloves, lab coat, and safety goggles.
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Hazard Considerations: Avoid inhalation, ingestion, and direct skin contact. Follow all institutional and local safety protocols when handling this compound.
Our laboratory ensures all materials are provided with comprehensive safety and technical datasheets, facilitating safe and effective usage for researchers.
WHY CHOOSE RESOLVEMASS LABORATORIES INC.
At ResolveMass Laboratories Inc., we focus on delivering high-quality, research-grade chemicals with consistent purity and performance. By sourcing ethyl 4-oxo-3,4-dihydrophthalazine-1-carboxylate through stringent quality control protocols, we support advanced pharmaceutical research, chemical synthesis, and R&D applications. Our services include:
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Reliable supply with guaranteed purity and consistency
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Technical support for custom applications and reactions
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Compliance with research-grade chemical standards
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Flexible quantities for small-scale or bulk research requirements





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