Ethylene-d4 carbonate | CAS 362049-63-6

OVERVIEW  of  Ethylene-d4 carbonate | CAS 362049-63-6

Ethylene-d4 carbonate is a deuterium-labeled version of ethylene carbonate (EC), a widely used organic solvent and electrolyte component in lithium-ion batteries. All four hydrogen atoms in the parent molecule are replaced by deuterium, yielding a heavier and spectroscopically distinct isotopologue. Despite the isotopic substitution, Ethylene-d4 carbonate maintains nearly identical physical and chemical properties to its non-deuterated form, making it ideal for comparative studies and isotopic tracing applications.

At ResolveMass Laboratories Inc., Ethylene-d4 carbonate is manufactured under tightly controlled synthesis and purification processes to guarantee isotopic consistency, low moisture content, and excellent stability. It is an essential reagent in the characterization of electrolyte behavior, degradation pathways, and reaction kinetics in electrochemical systems and materials research.

SUMMARY
Ethylene-d4 carbonate (CAS 362049-63-6) is a fully deuterated cyclic carbonate used as a stable isotope-labeled analog of ethylene carbonate. This compound serves as a valuable internal standard and tracer in analytical chemistry, particularly for nuclear magnetic resonance (NMR), gas chromatography–mass spectrometry (GC-MS), and liquid chromatography–mass spectrometry (LC-MS). At ResolveMass Laboratories Inc., Ethylene-d4 carbonate is supplied with ≥99 atom % D isotopic enrichment and ≥99% purity, ensuring superior analytical accuracy and reproducibility for advanced research in battery materials, chemical kinetics, and isotopic studies.

CHEMICAL INFORMATION

• Chemical Name: Ethylene-d4 carbonate

• Synonyms: 1,3-Dioxolan-2-one-d4; Fully deuterated ethylene carbonate

• CAS Number: 362049-63-6

• Molecular Formula: C₃D₄O₃

• Molecular Weight: 92.09 g/mol

• Isotopic Enrichment: ≥ 99 atom % D

• Chemical Structure: Five-membered cyclic carbonate with fully deuterated methylene groups

DESCRIPTION AND PROPERTIES
Ethylene-d4 carbonate is a polar aprotic solvent characterized by its high dielectric constant, low volatility, and strong solvating ability for lithium salts and polar compounds. The substitution of hydrogen with deuterium atoms alters its vibrational spectra, making it a powerful analytical tool in isotope effect studies, NMR spectroscopy, and spectroscopic calibration.

Due to its chemical inertness and thermal stability, Ethylene-d4 carbonate is widely used in electrochemical and materials research to investigate solvent–solute interactions, battery degradation mechanisms, and reaction kinetics without interference from hydrogen exchange.

APPLICATIONS  of  Ethylene-d4 carbonate | CAS 362049-63-6

1. Internal Standard for NMR and Mass Spectrometry:
   Ethylene-d4 carbonate is used as a stable isotope-labeled internal standard in quantitative NMR, LC-MS, and GC-MS analyses. Its mass shift and spectroscopic distinction enable accurate quantification and method validation.

2. Battery Electrolyte Research:
   As a deuterated analog of ethylene carbonate—a key solvent in lithium-ion batteries—Ethylene-d4 carbonate is essential for studying electrolyte composition, ion solvation, and SEI (solid electrolyte interphase) formation using spectroscopic and electrochemical methods.

3. Kinetic Isotope Effect Studies:
   The deuterium substitution enables researchers to probe mechanistic pathways and reaction rates in organic, catalytic, and electrochemical systems, offering insights into bond dissociation and reaction kinetics.

4. Spectroscopic Reference Material:
   Its distinct vibrational and NMR signatures make it an excellent reference compound for calibration and chemical shift assignment in both proton and deuterium NMR spectroscopy.

5. Tracer in Reaction Mechanisms:
   Ethylene-d4 carbonate is used as a non-radioactive tracer to elucidate solvent–solute interactions, decomposition routes, and molecular transport phenomena in complex matrices.

6. Analytical Calibration Standard:
   Owing to its purity and isotopic integrity, it serves as a calibration standard for GC-MS and LC-MS, ensuring precise quantitative analyses across environmental and materials testing laboratories.

ANALYTICAL ADVANTAGES

• Fully deuterated for clear isotopic differentiation (+4 Da mass shift)

• Ideal for use in NMR, GC-MS, and LC-MS applications

• Chemically and thermally stable under experimental conditions

• Minimal hydrogen exchange or isotope scrambling

• Provides accurate quantification and reproducible calibration

• Compatible with advanced spectroscopic and electrochemical studies

QUALITY AND MANUFACTURING
At ResolveMass Laboratories Inc., Ethylene-d4 carbonate is synthesized through high-purity deuterium exchange and controlled carbonylation reactions using advanced isotope labeling techniques. Each batch undergoes rigorous analytical verification using NMR spectroscopy, FTIR, and GC-MS to confirm isotopic enrichment, structural integrity, and chemical purity.

Quality assurance procedures follow international analytical and manufacturing standards, ensuring that every lot of Ethylene-d4 carbonate provides reproducible and traceable results. Researchers and analytical chemists trust ResolveMass Laboratories for its reliability, isotopic precision, and superior material consistency in deuterated solvent and reference compound supply.

CONCLUSION
Ethylene-d4 carbonate is a high-performance, fully deuterated cyclic carbonate ideal for analytical, electrochemical, and kinetic studies. With its precise isotopic labeling, exceptional purity, and reproducible performance, it enables accurate quantification, mechanistic insight, and method validation across a wide range of scientific disciplines. Offered by ResolveMass Laboratories Inc., Ethylene-d4 carbonate delivers the quality, stability, and analytical reliability required by research and industrial laboratories engaged in advanced materials and chemical investigations.

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