Indole-2,4,5,6,7-d5-3-acetic acid | CAS 76937-78-5

OVERVIEW  of  Indole-2,4,5,6,7-d5-3-acetic acid | CAS 76937-78-5

Indole-2,4,5,6,7-d5-3-acetic acid (CAS 76937-78-5) is a deuterium-labeled indole derivative featuring five deuterium atoms strategically placed on the aromatic ring. As a stable isotopologue of indole-3-acetic acid (IAA), it is widely used in plant hormone research, metabolic pathway elucidation, quantitative LC-MS/GC-MS analysis, and isotope-dilution assays. Its structural similarity to native IAA ensures accurate tracking, improved analytical precision, and reduced matrix interference in complex biological samples.

CHEMICAL INFORMATION
Chemical Name: Indole-2,4,5,6,7-d5-3-acetic acid
Synonyms: d5-Indole-3-acetic acid; Deuterated IAA
CAS Number: 76937-78-5
Molecular Formula: C₁₀H₄D₅NO₂
Molecular Weight: 180.22 g/mol
Isotopic Enrichment: ≥98 atom % D

APPLICATIONS  of  Indole-2,4,5,6,7-d5-3-acetic acid | CAS 76937-78-5

• Plant Hormone Research: Serves as a deuterated analog for studying auxin biosynthesis, transport, and degradation pathways.

• LC-MS / GC-MS Quantitation: Ideal as an internal standard for analyzing IAA in plant tissues, soil matrices, and biochemical samples.

• Metabolic & Tracer Studies: Enables precise tracking of auxin metabolism using isotope labeling approaches.

• Isotope-Dilution Assays: Enhances quantitation accuracy in regulatory, agricultural, and academic research settings.

• Environmental & Agricultural Science: Used to evaluate plant growth responses, stress signaling, and root development mechanisms.

SUMMARY
Indole-2,4,5,6,7-d5-3-acetic acid (CAS 76937-78-5) is a high-purity, deuterated analog of natural indole-3-acetic acid, optimized for mass spectrometry, plant biology research, and metabolic tracing. With five deuterium labels providing clear isotopic resolution, it delivers exceptional precision for auxin quantification and advanced biochemical studies.

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