Indole-d7 | CAS 73509-20-3

OVERVIEW  of  Indole-d7 | CAS 73509-20-3

Indole-d7 (CAS 73509-20-3) is a fully deuterated isotopologue of indole, containing seven deuterium atoms incorporated into the aromatic structure. As a fundamental heterocyclic compound found in biological systems, pharmaceuticals, natural products, and environmental matrices, indole is widely studied in chemistry and life sciences.
Its deuterated form, Indole-d7, is an essential internal standard for LC-MS and GC-MS analysis, enabling precise isotope-dilution quantitation, metabolic pathway tracing, impurity profiling, and reaction mechanism studies. Manufactured with high isotopic purity by ResolveMass Laboratories Inc., Indole-d7 supports advanced research applications across metabolomics, pharmaceutical development, environmental monitoring, and synthetic chemistry.

CHEMICAL INFORMATION
Chemical Name: Indole-d7
Synonyms: Hexadeuterated indole; Perdeuterated indole
CAS Number: 73509-20-3
Molecular Formula: C₈H₂D₇N
Molecular Weight: 124.19 g/mol
Isotopic Enrichment: ≥98 atom % D

APPLICATIONS  of  Indole-d7 | CAS 73509-20-3

• LC-MS/GC-MS Internal Standard: Enables precise quantitation of indole and related metabolites in biological and environmental samples.

• Metabolomics & Biochemical Research: Used for tracing indole metabolic pathways in microbial, plant, and mammalian systems.

• Pharmaceutical & Drug Discovery: Supports impurity profiling, stability studies, and reaction monitoring in indole-based drug synthesis.

• Environmental Analysis: Facilitates detection of indole derivatives in wastewater, soil, fermentation broths, and industrial samples.

• Synthetic Organic Chemistry: Acts as a labeled reference for mechanistic studies and isotopic effects in heterocyclic chemistry.

• Food & Aroma Chemistry: Assists in the quantification of indole compounds involved in flavor and fragrance analysis.

FEATURES & BENEFITS

• High Deuterium Incorporation: Provides excellent mass separation and enhanced analytical precision.

• Stable & Structurally Equivalent to Native Indole: Ensures reliable behavior in quantitative assays and metabolic studies.

• Versatile Analytical Compatibility: Suitable for LC-MS, GC-MS, and NMR workflows.

• High Purity for Sensitive Applications: Ideal for regulated labs, environmental testing, and pharmaceutical QC.

• Custom Labeling Available: ResolveMass Laboratories offers tailored indole derivatives upon request.

SUMMARY
Indole-d7 (CAS 73509-20-3) is a high-purity, fully deuterated indole used widely in LC-MS, GC-MS, metabolomics, pharmaceutical R&D, and environmental analysis. With seven deuterium atoms offering clear isotopic distinction, it is an essential internal standard and research tool for accurate quantitation and pathway elucidation.

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