Methyl Parathion-d8 | CAS 1219803-56-4

OVERVIEW  of  Methyl Parathion-d8 | CAS 1219803-56-4

Methyl Parathion-d8 is a highly pure, fully characterized deuterium-labeled analogue of the organophosphate insecticide methyl parathion. Incorporating eight deuterium atoms into its molecular structure, this isotopologue is specifically engineered to deliver exceptional mass spectral separation, improved analytical stability, and reproducible quantitation in complex environmental and biological matrices. It is an essential reference material for laboratories performing pesticide residue detection, environmental risk assessment, and regulatory compliance testing.

CHEMICAL INFORMATION

• Chemical Name: Methyl Parathion-d8

• CAS Number: 1219803-56-4

• Molecular Formula: C8H3D8NO5PS

• Isotopic Enrichment: ≥98% deuterium incorporation

• Purity: ≥98% (typical analytical-grade standard)

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STRUCTURAL SIGNIFICANCE
Deuterium substitution enhances the compound’s:

• Mass spectrometric detectability due to predictable m/z shifts

• Chemical stability, minimizing degradation during storage and analysis

• Differentiation from native methyl parathion, crucial for accurate isotope-dilution quantification

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APPLICATIONS  of  Methyl Parathion-d8 | CAS 1219803-56-4
Methyl Parathion-d8 is widely used in LC-MS/MS and GC-MS workflows as an internal standard or tracer for:

• Environmental monitoring: soil, sediment, groundwater, drinking water

• Agricultural residue analysis: crops, food commodities, grain storage environments

• Toxicological and exposure studies: metabolism, biomonitoring, kinetic profiling

• Regulatory compliance testing: EPA, EU, and Codex pesticide residue programs

• Method development and validation: calibration curves, recovery studies, matrix-effect evaluation.

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  KEY FEATURES 

• High isotopic purity ensures reliable differentiation from unlabeled analyte

• Excellent compatibility with multi-residue pesticide panels

• Enhances quantitative accuracy in trace-level detection

• Suitable for long-term stability studies and proficiency testing.

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QUALITY & COMPLIANCE

• Manufactured under stringent quality systems

• Accompanied by a Certificate of Analysis (CoA) with detailed isotopic data

• Ideal for GLP, ISO/IEC 17025, and regulatory pesticide testing laboratories

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SUMMARY

Methyl Parathion-d8 is a deuterium-labeled analogue of methyl parathion designed for high-precision LC-MS/MS and GC-MS pesticide residue analysis. With eight deuterium atoms providing clear mass spectral separation and outstanding stability, it serves as an ideal internal standard for environmental monitoring, food safety testing, exposure studies, and regulatory method validation. Its high isotopic enrichment and purity ensure accurate quantitation in even the most complex matrices.

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