Ethanol-1,1,2,2-d4-amine | CAS 85047-08-1

OVERVIEW  of  Ethanol-1,1,2,2-d4-amine | CAS 85047-08-1
Ethanol-1,1,2,2-d₄-amine (CAS 85047-08-1) is a deuterium-labeled analog of ethanolamine, in which all hydrogen atoms on the carbon backbone are replaced with deuterium. This stable isotope-labeled compound is chemically identical to regular ethanolamine but has an increased molecular mass due to deuterium substitution. It is widely utilized in mass spectrometry (MS), nuclear magnetic resonance (NMR), and biochemical tracer studies for quantification and structural elucidation. The deuterated form provides enhanced analytical accuracy by minimizing spectral overlap and improving isotopic discrimination in complex biological or chemical systems.

CHEMICAL INFORMATION

• Name: Ethanol-1,1,2,2-d₄-amine

• Molecular Formula: C₂H₃D₄NO

• Molecular Weight: 65.11 g/mol

• CAS Number: 85047-08-1

• Isotopic Enrichment: ≥ 98 atom % D

• Chemical Class: Deuterated alkanolamine

• Solubility: Fully miscible with water, alcohol, and polar organic solvents

APPLICATIONS  of  Ethanol-1,1,2,2-d4-amine | CAS 85047-08-1

• Mass Spectrometry (MS):
  Used as an internal standard or labeled analog for quantitative analysis of ethanolamine and related compounds in environmental, biological, or pharmaceutical samples.

• Nuclear Magnetic Resonance (NMR):
  Employed in structural and dynamic studies where deuteration reduces proton coupling interference, improving spectral resolution and simplifying analysis.

• Metabolic and Biochemical Research:
  Serves as a stable isotope tracer to study ethanolamine metabolism, biosynthesis of phospholipids, and related biochemical transformations.

• Analytical Chemistry and Calibration:
  Used in method validation and isotopic dilution analysis, providing precise quantification and tracking in complex analytical workflows.

ADVANTAGES  of  Ethanol-1,1,2,2-d4-amine | CAS 85047-08-1

• High deuterium enrichment ensures isotopic purity and analytical consistency.

• Non-radioactive and stable under standard laboratory conditions.

• Chemically equivalent to ethanolamine, allowing direct substitution in experimental setups.

• Enhances spectral clarity in NMR and improves isotopic accuracy in MS-based assays.

HANDLING AND SAFETY

• Handling: Use in a well-ventilated area; avoid contact with skin, eyes, and clothing.

• Storage: Store in a cool, dry environment at 2–8 °C; protect from light and moisture.

• Safety: May cause irritation to skin and eyes; appropriate protective equipment such as gloves and goggles should be worn.

• Disposal: Dispose of in accordance with institutional and local environmental regulations.

SUMMARY
Ethanol-1,1,2,2-d₄-amine (CAS 85047-08-1) is a high-purity, deuterium-enriched ethanolamine analog commonly used in mass spectrometry, NMR spectroscopy, and isotope tracer studies. Its stable isotopic labeling makes it a preferred choice for quantitative and mechanistic research, ensuring precision, reproducibility, and clarity in analytical and biochemical investigations.